Fig. 2

Effects of BBR and lovastatin on the liver function of hyperlipidemic hamsters. (a) Lovastatin (30 mg/kg/day) increased the serum ALT level by 2.0-fold at day 10 compared with the HFD control group at day 0, whereas the BBR (100 mg/kg/day) group showed no significant differences over the entire period. (b) Lovastatin (30 mg/kg/day) elevated the serum AST level by 2.1-fold at day 10 compared with the HFD control group at day 0, whereas the BBR (100 mg/kg/day) group showed no significant differences over the entire period. (c) There were no significant differences in the serum GGT levels in any of the groups. The data are shown as the mean ± SD. **P < 0.01 and ***P < 0.001 vs the HFD controls; ^## P < 0.01 and ^### P < 0.001 vs the BBR-treated HFD hamsters (100 mg/kg/day).