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Table 2 Association of SNPs with CFS

From: Polymorphism in COMT is associated with IgG3 subclass level and susceptibility to infection in patients with chronic fatigue syndrome

SNP

n

Minor −/−

Hetero −/+

Major +/+

Genotypic frequencies (%)

Allelic frequencies (%)

p value

CRHR1 rs12944712

    

Met/Met

Met/Val

Val/Val

G

A

 

 Healthy

76

26

38

12

0.34

0.50

0.16

0.59

0.41

0.6189

 CFS

74

27

34

13

0.36

0.46

0.18

0.59

0.41

 

COMT rs4680

    

G/G

G/A

A/A

G

A

 

 Healthy

76

18

45

13

0.24

0.59

0.17

0.53

0.47

0.7439

 CFS

74

22

37

15

0.30

0.50

0.20

0.55

0.45

 

FKBP5 rs1360780

    

T/T

T/C

C/C

T

C

 

 Healthy

76

8

29

39

0.11

0.38

0.51

0.30

0.70

0.6396

 CFS

74

5

33

36

0.07

0.45

0.49

0.29

0.71

 
  1. Allelic discrimination PCR was performed for 74 CFS patients and 76 healthy controls.