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Table 2 Association of SNPs with CFS

From: Polymorphism in COMT is associated with IgG3 subclass level and susceptibility to infection in patients with chronic fatigue syndrome

SNP n Minor −/− Hetero −/+ Major +/+ Genotypic frequencies (%) Allelic frequencies (%) p value
CRHR1 rs12944712      Met/Met Met/Val Val/Val G A  
 Healthy 76 26 38 12 0.34 0.50 0.16 0.59 0.41 0.6189
 CFS 74 27 34 13 0.36 0.46 0.18 0.59 0.41  
COMT rs4680      G/G G/A A/A G A  
 Healthy 76 18 45 13 0.24 0.59 0.17 0.53 0.47 0.7439
 CFS 74 22 37 15 0.30 0.50 0.20 0.55 0.45  
FKBP5 rs1360780      T/T T/C C/C T C  
 Healthy 76 8 29 39 0.11 0.38 0.51 0.30 0.70 0.6396
 CFS 74 5 33 36 0.07 0.45 0.49 0.29 0.71  
  1. Allelic discrimination PCR was performed for 74 CFS patients and 76 healthy controls.