Skip to main content

Advertisement

Table 3 Correlation between the expression level of microRNAs miR-296-5p, miR-452, miR-183* and miR-200c and the clinical and pathological characteristics of the LSCC patients enrolled in the study

From: Expression of miR-296-5p as predictive marker for radiotherapy resistance in early-stage laryngeal carcinoma

Variable Categories Number of cases miR-296-5p miR-452 miR-183* miR-200c
Low High Low High Low High Low High
n (%) n (%) n (%) n (%) n (%) n (%) n (%) n (%)
Age (years) ≤60 years 16 6 (35.3) 10 (58.8) 8 (47.1) 8 (47.1) 8 (47.1) 8 (47.1) 8 (50.0) 8 (47.1)
>60 years 18 11 (64.7) 7 (41.2) 9 (52.9) 9 (52.9) 9 (52.9) 9 (52.9) 8 (50.0) 9 (52.9)
p (2-sided)   NS NS NS NS
Gender Female 4 2 (11.8) 2 (11.8) 2 (11.8) 2 (11.8) 2 (11.8) 2 (11.8) 2 (12.5) 2 (12.5)
Male 30 15 (88.2) 15 (88.2) 15 (88.2) 15 (88.2) 15 (88.2) 15 (88.2) 14 (87.5) 15 (88.2)
p (2-sided)   NS NS NS NS
Smoking No 3 0 (0) 3 (17.6) 1 (5.9) 2 (11.8) 0 (0) 3 (17.6) 2 (12.5) 1 (9.1)
Yes 31 17 (100) 14 (82.4) 16 (94.1) 15 (88.2) 17 (100) 14 (82.4) 14 (87.5) 16 (94.1)
p (2-sided)   NS NS NS NS
Tumor site* Glottic 27 15 (88.2) 12 (70.6) 14 (82.4) 13 (76.5) 14 (82.4) 13 (76.5) 14 (87.5) 12 (70.6)
Supraglottic 7 2 (11.8) 5 (29.4) 3 1 (7.6) 4 (23.5) 3 (17.6) 4 (23.5) 2 (12.5) 5 (29.4)
p (2-sided)   NS NS NS NS
Tumor stage I 16 7 (41.2) 9 (52.9) 9 (52.9) 7 (41.2) 7 (41.2) 9 (52.9) 7 (43.8) 9 (52.9)
II 18 10 (58.8) 8 (47.1) 8 (47.1) 10 (58.8) 10 (58.8) 8 (47.1) 9 (56.2) 8 (47.1)
p (2-sided)   NS NS NS NS
Radiosensibility Sensivite 14 11 (64.7) 3 (17.6) 8 (47.1) 6 (35.3) 9 (52.9) 5 (29.4) 7 (43.8) 7 (41.2)
Resistant 20 6 (35.3) 14 (82.4) 9 (52.9) 11 (64.7) 8 (47.1) 12 (70.6) 9 (56.2) 10 (58.8)
p (2-sided)   0.01 NS NS NS
  1. Italic value indicates statistical significance at p < 0.05.
  2. p (Fisher’s exact); NS (p > 0.05).