Fig. 6

Histology of H&E stained lung sections showing suppression of inflammation by esomeprazole. Lung inflammation was induced by injuring animals with bleomycin instillation. The animals were treated with vehicle or low dose esomeprazole (prophylactic) for up to 28 days. Subsequently, lung tissues were harvested and stained with H&E to assess overall lung morphology and inflammation. Lower panel shows average lung inflammation score of 10 animals per group. No bleomycin sham group was included as control. *p < 0.05 compared to vehicle. Representative images are shown.