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Table 3 Correlation between clinical characteristics and PIK3CA mutations

From: Epidermal growth factor receptor pathway mutation and expression profiles in cervical squamous cell carcinoma: therapeutic implications

Characteristics

n = 95

PIK3CA mutant-type

PIK3CA wild-type

P value*

No. of patient (n = 19)

No. of patient (n = 76)

Mean age (SD)

49.7 (13.2)

56.6 (10.7)

48.2 (13.7)

0.007

FIGO stage

 Stage I

84 (88.4%)

16 (16.8%)

68 (71.6%)

0.688

 Stage II–III

11 (11.6%)

3 (3.2%)

8 (8.4%)

Tumor size

 ≤2 cm

11

1

10

0.433

 >2–5 cm

69

16

53

 >5 cm

15

2

13

Lymphnode

 Positive

17

5

12

0.337

 Negative

61

11

50

 No data

17

  

Histology

 Well

16 (16.8%)

2 (2.1%)

14 (14.7%)

0.547

 Moderately

65 (68.4%)

13 (13.7%)

52 (54.7%)

 Poorly

14 (14.7%)

4 (4.2%)

10 (10.5%)

  1. Italic value indicates statistically significant.
  2. * Pearson chi square and Fisher’s exact test.