From: Altered microRNAs expression profiling in cumulus cells from patients with polycystic ovary syndrome
 | P value | Ratio | |
---|---|---|---|
Pathways | |||
 MAPK signaling pathway | 1.21E−60 | 160 | 287 |
 Wnt signaling pathway | 4.87E−49 | 104 | 159 |
 Insulin signaling pathway | 1.93E−20 | 90 | 230 |
 Notch signaling pathway | 1.09E−18 | 36 | 53 |
 p53 signaling pathway | 3.02E−18 | 46 | 83 |
 GnRH signaling pathway | 3.66E−14 | 60 | 153 |
 Hedgehog signaling pathway | 1.03E−13 | 35 | 65 |
Networks | |||
 Regulation of actin cytoskeleton | 1.91E−30 | 125 | 303 |
 Focal adhesion | 1.34E−26 | 124 | 324 |
 Cell cycle | 8.90E−23 | 87 | 204 |
 Oocyte meiosis | 1.55E−19 | 70 | 159 |
 ECM-receptor interaction | 3.62E−19 | 57 | 115 |
 Gap junction | 3.09E−16 | 61 | 144 |
 Pancreatic secretion | 2.98E−12 | 61 | 171 |
 Progesterone-mediated oocyte maturation | 1.66E−10 | 52 | 147 |
Diseases | |||
 Pancreatic cancer | 8.85E−14 | 42 | 88 |
 Type I diabetes mellitus | 1.28E−11 | 30 | 57 |
 Endometrial cancer | 1.56E−09 | 31 | 70 |
 Type II diabetes mellitus | 4.05E−08 | 24 | 52 |
 Maturity onset diabetes of the young | 8.60E−08 | 17 | 30 |
Metabolisms | |||
 Glycosaminoglycan biosynthesis-heparan sulfate | 6.85E−17 | 23 | 26 |
 N-Glycan biosynthesis | 5.31E−16 | 32 | 49 |
 Starch and sucrose metabolism | 4.34E−13 | 33 | 61 |
 Amino sugar and nucleotide sugar metabolism | 9.32E−09 | 24 | 49 |
 Fructose and mannose metabolism | 2.38E−08 | 22 | 44 |
 Glycine, serine and threonine metabolism | 4.03E−08 | 22 | 45 |
 Galactose metabolism | 6.36E−07 | 16 | 30 |
 Steroid biosynthesis | 9.98E−05 | 10 | 19 |