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Fig. 1 | Journal of Translational Medicine

Fig. 1

From: A novel placental like alkaline phosphate promoter driven transcriptional silencing combined with single chain variable fragment antibody based virosomal delivery for neoplastic cell targeting

Fig. 1

Cervical cancer specific expression of PLAP promoter/enhancer system. a–c 48 h after transfection, luciferase activity by enhancer/promoter system was observed only in PLAP positive cervical cancer cell lines HeLa, CaSki, and SiHa. It was highest in case of NFκBEn–Pr+24-luc. SV40-luc showed nonspecific tissue expression. d and e No, luciferase activity was observed through PLAP promoter/enhancer systems in non-PLAP HepG2 and CHO cells. Luciferase activity observed by NFκBEn–Pr+24-luc was significantly higher when compared to that by PLAPPr+24-luc (p = 0.022).

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