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Table 3 Circulating CD133+ and CD34+ HSC in GFD-treated coeliac patients during follow-up

From: Circulating hematopoietic stem cells and putative intestinal stem cells in coeliac disease

Timing

T0

T7d

T1m

T3m

T6m

T12m

T24m

HSC

CD133

CD34

CD133

CD34

CD133

CD34

CD133

CD34

CD133

CD34

CD133

CD34

CD133

CD34

Mean %

0.020

0.166

0.745

2.988

0.520

0.626

0.120

0.143

0.091

0.106

0.028

0.042

0.011

0.029

SD %

0.006

0.063

0.125

0.407

0.092

0.093

0.047

0.019

0.024

0.017

0.020

0.008

0.004

0.012

p value versus ctrls

<0.05

<0.05

<0.05

<0.05

<0.05

<0.05

<0.05

<0.05

<0.05

<0.05

NS

NS

NS

NS

p value versus T0 CD

  

<0.05

<0.05

<0.05

<0.05

<0.05

NS

<0.05

<0.05

NS

<0.05

<0.05

<0.05

  1. The last two rows represent the p values of the comparison between controls and active CD patients at the various time-points.
  2. SD standard deviation, T0 baseline, T7 7 days following gluten removal from diet, T1m, T3m, T6m, T12m and T24m 1, 3, 6, 12 and 24 months following gluten removal from diet, respectively, NS non-significant.