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Table 1 Patient and HV characteristics

From: IL-17/IL-10 double-producing T cells: new link between infections, immunosuppression and acute myeloid leukemia

 

HV

AML

No. patients

30

30

Gender

  

 Male

15 (50%)

14 (47%)

 Female

15 (50%)

16 (53%)

Median age, years (range)

63 (38–87)

68 (35–85)

Subtype according to FAB classification

 M0–M1

 

6 (20%)

 M2

 

9 (30%)

 M4

 

4 (13.3%)

 M5

 

9 (30%)

 M6

 

1 (3.3%)

 M7

 

1 (3.3%)

Karyotype

 Normal

 

14 (47%)

 Undefined

 

4 (13%)

 Complex

 

3 (10%)

Trisomy chr 8

 

3 (10%)

 t(8–21)

 

2 (7%)

 Tetrasomy chr 21

 

1 (3%)

 Inv chr 3

 

1 (3%)

 Del chr 7

 

1 (3%)

 Del chr 20

 

1 (3%)

Molecular mutations

 FLT3/NPM wt

 

17 (57%)

 FLT3 ITD

 

4 (13%)

 FLT3 mut NPM mut

 

3 (10%)

 FLT3 mut NPM wt

 

1 (3%)

 FLT3 wt NPM mut

 

1 (3%)

 AML-ETO

 

2 (7%)

 Undefined

 

2 (7%)

  1. FAB French-American-British, chr chromosome, t translocation, Inv inversion, Del deletion, wt wild type, mut mutated.