| HV | AML |
---|---|---|
No. patients | 30 | 30 |
Gender | Â | Â |
 Male | 15 (50%) | 14 (47%) |
 Female | 15 (50%) | 16 (53%) |
Median age, years (range) | 63 (38–87) | 68 (35–85) |
Subtype according to FAB classification | ||
 M0–M1 |  | 6 (20%) |
 M2 |  | 9 (30%) |
 M4 |  | 4 (13.3%) |
 M5 |  | 9 (30%) |
 M6 |  | 1 (3.3%) |
 M7 |  | 1 (3.3%) |
Karyotype | ||
 Normal |  | 14 (47%) |
 Undefined |  | 4 (13%) |
 Complex |  | 3 (10%) |
Trisomy chr 8 | Â | 3 (10%) |
 t(8–21) |  | 2 (7%) |
 Tetrasomy chr 21 |  | 1 (3%) |
 Inv chr 3 |  | 1 (3%) |
 Del chr 7 |  | 1 (3%) |
 Del chr 20 |  | 1 (3%) |
Molecular mutations | ||
 FLT3/NPM wt |  | 17 (57%) |
 FLT3 ITD |  | 4 (13%) |
 FLT3 mut NPM mut |  | 3 (10%) |
 FLT3 mut NPM wt |  | 1 (3%) |
 FLT3 wt NPM mut |  | 1 (3%) |
 AML-ETO |  | 2 (7%) |
 Undefined |  | 2 (7%) |