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Table 1 Clinicopathological characteristics of the patients according to the breast cancer stromal histologic phenotype

From: Expression of cancer-associated fibroblast related proteins in metastatic breast cancer: an immunohistochemical analysis

Parameter Total N = 132 (%) Desmoplastic type n = 38 (%) Inflammatory type n = 9 (%) Pauci-stroma type n = 45 (%) Sclerotic type n = 40 (%) p value
Age (years)       0.600
 ≤50 68 (51.5) 21 (55.3) 5 (55.6) 25 (55.6) 17 (42.5)  
 >50 64 (48.5) 17 (44.7) 4 (44.4) 20 (44.4) 23 (57.5)  
ER       0.339
 Negative 63 (47.7) 20 (52.6) 6 (66.7) 22 (48.9) 15 (37.5)  
 Positive 69 (52.3) 18 (47.4) 3 (33.3) 23 (51.1) 25 (62.5)  
PR       0.060
 Negative 91 (68.9) 28 (73.7) 7 (77.8) 35 (77.8) 21 (52.5)  
 Positive 41 (31.1) 10 (26.3) 2 (22.2) 10 (22.2) 19 (47.5)  
HER-2       0.370
 Negative 89 (67.4) 28 (73.7) 4 (44.4) 29 (64.4) 28 (70.0)  
 Positive 43 (32.6) 10 (26.3) 5 (55.6) 16 (35.6) 12 (30.0)  
Molecular subtypes       0.063
 Luminal A 47 (35.6) 15 (39.5) 3 (33.3) 12 (26.7) 17 (42.5)  
 Luminal B 23 (17.4) 3 (7.9) 0 (0.0) 11 (24.4) 9 (22.5)  
 HER-2 27 (20.5) 7 (18.4) 5 (55.6) 8 (17.8) 7 (17.5)  
 TNBC 35 (26.5) 13 (34.2) 1 (11.1) 14 (31.1) 7 (17.5)  
Ki-67 LI (%)       0.139
 ≤14 91 (68.9) 31 (81.6) 6 (66.7) 26 (57.8) 28 (70.0)  
 >14 41 (31.1) 7 (18.4) 3 (33.3) 19 (42.2) 12 (30.0)  
Metastasis site       < 0.001
 Bone 32 (24.2) 18 (47.4) 0 (0.0) 4 (8.9) 10 (25.0)  
 Brain 38 (28.8) 3 (7.9) 2 (22.2) 25 (55.6) 8 (20.0)  
 Liver 10 (7.6) 0 (0.0) 0 (0.0) 0 (0.0) 10 (25.0)  
 Lung 52 (39.4) 17 (44.7) 7 (77.8) 16 (35.6) 12 (30.0)  
Patients death 44 (33.3) 15 (39.5) 3 (33.3) 14 (31.1) 12 (30.0) 0.815
  1. Italic value indicates statistically significant (p < 0.05).
  2. TNBC triple negative breast cancer.