Treatment condition
|
BV-2
|
IMA2.1
|
BV-2
|
IMA2.1
|
---|
Virus progenya
|
VACV-mediated cell deathb
|
---|
M2 phenotype
|
w/o
|
+
|
0
|
+
|
−
|
IL-4
|
+
|
nt
|
+
|
−
|
M1 phenotype
|
IFN-γ
|
−
|
−
|
−
|
−
|
IFN-γ + LPS
|
−
|
−
|
−
|
−
|
LPS
|
−
|
−
|
−
|
−
|
-
nt not tested, w/o without stimulation.
-
aVirus progeny (24 and 72 hpi) related to the infection medium was determined by standard plaque assays. [+] indicates an increase of the virus titer from the infection medium, [0] virus titer at the same level as the infection medium, [−] virus titer below the infection medium.
-
bVACV-mediated cell death was related to uninfected controls (24–72 hpi) and measured by MTT cell survival assays. [+] more than 50% of cells were killed by LIVP 1.1.1 [−] less than 50% of cells were killed by LIVP 1.1.1.