Skip to main content

Table 1 Effects of febuxostat on left ventricular parameters post-I/R myocardial injury

From: Febuxostat pretreatment attenuates myocardial ischemia/reperfusion injury via mitochondrial apoptosis

 

Baseline

7-day post I/R

I/R (n = 7)

I/R + FEB (n = 7)

I/R + ALL (n = 7)

I/R (n = 7)

I/R + FEB (n = 7)

I/R + ALL (n = 7)

LVEDD (mm)

3.46 ± 0.05

3.46 ± 0.04

3.47 ± 0.04

3.97 ± 0.11

3.94 ± 0.08

3.96 ± 0.10

LVESD (mm)

2.26 ± 0.02

2.27 ± 0.02

2.25 ± 0.02

2.92 ± 0.07

2.74 ± 0.07#

2.80 ± 0.09#

FS (%)

34.6 ± 0.01

34.47 ± 0.01

35.27 ± 0.03

26.43 ± 0.03

30.39 ± 0.02#

28.77 ± 0.05#

EF (%)

66.6 ± 0.98

65.91 ± 1.42

65.16 ± 1.22

37.66 ± 1.30

41.93 ± 1.52#

39.73 ± 4.08#

  1. Values are mean ± SD.
  2. LVEDD left ventricular end-diastolic diameter, LVESD left ventricular end-systolic diameter, FS fractional shortening, EF ejection fraction, I/R ischemia/reperfusion.
  3. # P < 0.05 vs. I/R.
Back to article page

Journal of Translational Medicine

ISSN: 1479-5876

Contact us