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Table 1 Effects of febuxostat on left ventricular parameters post-I/R myocardial injury

From: Febuxostat pretreatment attenuates myocardial ischemia/reperfusion injury via mitochondrial apoptosis

  Baseline 7-day post I/R
I/R (n = 7) I/R + FEB (n = 7) I/R + ALL (n = 7) I/R (n = 7) I/R + FEB (n = 7) I/R + ALL (n = 7)
LVEDD (mm) 3.46 ± 0.05 3.46 ± 0.04 3.47 ± 0.04 3.97 ± 0.11 3.94 ± 0.08 3.96 ± 0.10
LVESD (mm) 2.26 ± 0.02 2.27 ± 0.02 2.25 ± 0.02 2.92 ± 0.07 2.74 ± 0.07# 2.80 ± 0.09#
FS (%) 34.6 ± 0.01 34.47 ± 0.01 35.27 ± 0.03 26.43 ± 0.03 30.39 ± 0.02# 28.77 ± 0.05#
EF (%) 66.6 ± 0.98 65.91 ± 1.42 65.16 ± 1.22 37.66 ± 1.30 41.93 ± 1.52# 39.73 ± 4.08#
  1. Values are mean ± SD.
  2. LVEDD left ventricular end-diastolic diameter, LVESD left ventricular end-systolic diameter, FS fractional shortening, EF ejection fraction, I/R ischemia/reperfusion.
  3. # P < 0.05 vs. I/R.
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Journal of Translational Medicine

ISSN: 1479-5876

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