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Table 2 Frequencies of the alleles and genotypes of the A20 polymorphisms in RA patients (case) and healthy individuals (control)

From: Characteristics of A20 gene polymorphisms and clinical significance in patients with rheumatoid arthritis

SNPs Genotype frequency n (%) Allele frequency n (%)
Major homozygote Heterozygote Minor homozygote   Major allele Minor allele
rs5029937 GG GT TT   G T
 Case 48 (96.0) 2 (4.0) 0 (0)   98 (98.0) 2 (2.0)
 Control 28 (93.3) 2 (6.7) 0 (0)   58 (96.7) 2 (3.3)
 p-value 1.000    1.000
rs3799491 GG GA AA GA/AA G A
 Case 38 (76.0) 11 (22.0) 1 (2.0) 12 (24) 87 (87.0) 13 (13.0)
 Control 21 (70.0) 9 (30.0) 0 (0) 9 51 (85.0) 9 (15.0)
 p-value 0.454 1.000* 0.555 0.722
rs598493 CC TC TT   C T
 Case 44 (88.0) 6 (12.0) 0 (0)   94 (94.0) 6 (6.0)
 Control 26 (86.7) 4 (13.3) 0 (0)   56 (93.3) 4 (6.7)
 p-value 1.000    1.000
rs2307859 –/CCT Wild type     
 Case 48 (96.0) 2 (4.0)     
 Control 30 (100) 0 (0)     
 p-value 0.525*     
rs146534657 AA AG GG   A G
 Case 48 (96.0) 2 (4.0) 0 (0)   98 (98.0) 2 (2.0)
 Control 30 (100) 0 (0) 0 (0)   60 (100) 0 (0)
 p-value 0.525*    0.528*
rs2230926 TT TG GG   T G
 Case 47 (94.0) 3 (6.0) 0 (0)   97 (97.0) 3 (3.0)
 Control 28 (93.3) 2 (6.7) 0 (0)   58 (96.7) 2 (3.3)
 p-value 1.000    1.000
rs661561 CC AC AA AC/AA C A
 Case 41 (82.0) 8 (16.0) 1 (2.0) 9 (18) 90 (90.0) 10 (10.0)
 Control 24 (80) 6 (20) 0 (0) 6 (20) 54 (90.0) 6 (10.0)
 p-value 0.678 1.000* 0.824 1.000
rs582757 TT CT CC   T C
 Case 44 (88.0) 6 (12.0) 0 (0)   94 (94.0) 6 (6.0)
 Control 26 (86.7) 4 (13.3) 0 (0)   56 (93.3) 4 (6.7)
 p-value 1.000    1.000
  1. n number of participants.
  2. * Fisher’s exact p value.
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