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Table 1 Physical and biochemical characteristics of the control and diabetic mice with or without anthocyanin treatment at the end of the 12-week experimental period

From: Anthocyanin-rich Seoritae extract ameliorates renal lipotoxicity via activation of AMP-activated protein kinase in diabetic mice

  db/m control db/m ATC db/db control db/db ATC
Body weight (g) 31.6 ± 2.2 31.3 ± 1.9 59.8 ± 5.7** 41.4 ± 5.1**
Kidney weight (g) 0.2 ± 0.01 0.2 ± 0.02 0.26 ± 0.01* 0.24 ± 0.04*
Food intake (g/d) 1.2 ± 1.1 1.3 ± 0.8 4.0 ± 0.1** 5.7 ± 2.1**
FBS (mg/dL) 136 ± 21 142 ± 17 577 ± 49** 552 ± 66**
HbA1c (%) 4.1 ± 0.1 3.9 ± 0.3 13.0 ± 1.2** 11.8 ± 2.5**
NEFA (mEq/L) 1.01 ± 0.08 0.98 ± 0.08 1.92 ± 0.25** 1.04 ± 0.13
Triglycerides (mg/dL) 40.1 ± 8.9 20.8 ± 9.8 71.9 ± 13.7** 28.0 ± 20.0
Total cholesterol (mg/dL) 26.6 ± 5.9 30.3 ± 1.8 41.8 ± 9.4* 29.4 ± 2.6
24-h albuminuria (µg) 11.4 ± 2.9 4.4 ± 2.7 169.4 ± 74.5** 62.0 ± 37.0
Urine volume (mL) 0.4 ± 0.5 0.4 ± 0.4 10.6 ± 4.9** 10.7 ± 4.2**
  1. Data are mean ± SD (n = 6–8 per group).
  2. FBS fasting blood sugar.
  3. p < 0.05 and ** p < 0.001 compared with the other groups.