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Figure 2 | Journal of Translational Medicine

Figure 2

From: Anthocyanin-rich Seoritae extract ameliorates renal lipotoxicity via activation of AMP-activated protein kinase in diabetic mice

Figure 2

Phospho-Thr172 AMPK, total AMPK, PPARα, PPARγ, phospho-ACC, total ACC, SREBP-1, and intra-renal lipid levels in the renal cortex of db/m and db/db mice with or without anthocyanin treatment. Protein lysates (30 μg) from the renal cortex were separated by SDS-PAGE and analysed by western blotting. a Representative western blots for phospho-Thr172 AMPK, total AMPK, PPARα, PPARγ, phospho-ACC, total ACC, SREBP-1, and β-actin. bf Quantitative analyses for phospho-Thr172 AMPK/total AMPK (b), PPARα/β-actin (c), PPARγ/β-actin (d), phospho-ACC/total ACC (e), and SREBP-1/β-actin (f). *p < 0.05 and **p < 0.01 vs. db/m control, db/m ATC, and db/db ATC mice. gi Quantitative analyses of intra-renal NEFA (g), triglyceride (h), and total cholesterol (i) concentrations. *p < 0.05 and **p < 0.01 vs. db/m control, db/m ATC, and db/db ATC mice.

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