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Figure 3 | Journal of Translational Medicine

Figure 3

From: Effects of hydrogen-rich saline on early acute kidney injury in severely burned rats by suppressing oxidative stress induced apoptosis and inflammation

Figure 3

Assessment of oxidative stress and antioxidant enzyme activities in the kidneys of burned rats and the effects of HS treatment. After burn injury, the renal tissues of the rats displayed significant elevations in the ORP value in the different groups compared with the Sham group (b). Additionally, the MDA levels in the rat renal tissues presented remarkable augmentations after burn (a), with simultaneous declines in the activities of endogenous antioxidant enzymes (SOD, GSH-Px, and CAT) (c–d). Following the application of HS for different lengths of time post burn, significant reductions were observed in the ORP and MDA levels, and antioxidant enzyme activities increased (a–e). The sample size was n = 8 for each group. The results were expressed as the means ± SEMs. *p < 0.05, **p < 0.01, vs Burn + saline; #p < 0.05, ##p < 0.01, vs Sham.

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