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Table 3 Comparison of carrier frequency of KIR genes in three ethnic minority populations in China

From: KIR diversity in three ethnic minority populations in China

KIR

Tibetan

Kazakh

Uyghur

P values

N = 224

N = 125

N = 130

Tibetan vs Kazakh

Tibetan vs Uyghur

Kazak vs Uyghur

%CF(n)

%CF(n)

%CF(n)

A haplotype associated

 2DL1

99.1 (222)

98.4 (123)

98.5 (128)

   

 2DL3

98.7 (221)

95.2 (119)

92.3 (120)

 

0.0056

 

 3DL1

97.3 (218)

95.2 (119)

91.5 (119)

 

0.0028

 

 2DS4-f

86.6 (194)

64.8 (81)

62.3 (81)

<0.0001

<0.0001

 

 2DS4-v

29.5 (66)

59.2 (74)

60.8 (79)

<0.0001

<0.0001

 

B haplotype associated

 2DL2

24.6 (35)

33.6 (42)

43.8 (57)

 

0.0003

 

 2DL5

38.4 (86)

47.2 (59)

59.2 (77)

 

0.0002

 

 2DS1

36.2 (81)

39.2 (49)

40.8 (53)

   

 2DS2

25.0 (56)

36.8 (46)

46.9 (61)

0.0277

<0.0001

 

 2DS3

12.5 (28)

23.2 (29)

33.9 (44)

0.0146

<0.0001

 

 2DS5

31.3 (70)

33.6 (42)

33.1 (43)

   

 3DS1

35.3 (79)

36.0 (45)

39.2 (51)

   

Framework/pseudogenes

 2DL4

100 (224)

100 (125)

100 (130)

   

 3DL2

100 (224)

100 (125)

100 (130)

   

 3DL3

100 (224)

100 (125)

100 (130)

   

 2DP1

99.1 (222)

98.4 (123)

100 (130)

   

 3DP1

100 (224)

100 (125)

100 (130)

   
  1. Frequency (%CF) of carriers of each gene is expressed as a percentage and defined as the number of donors carrying the gene (n) divided by the number of donors studied (N) in the given populations. The p values are given only for those pairwise comparisons indicating significant (P < 0.05) difference.