Figure 2

Distribution of ancestral ‘C’ allele (rs1063856) frequency of VWF gene associated with thrombosis in diverse IGVC and HGDP-CEPH populations. a Frequency in the 24 IGV populations. TB-N-IP1, a population from high altitude has fixation for the derived allele. b Spatial frequency map of rs1063856 in the HGDP-CEPH panel of 55 populations retrieved from HGDP selection browser. There is a clinal variation in the frequency of derived allele as populations moved out of Africa.