From: Natural killer (NK) cell profiles in blood and tumour in women with large and locally advanced breast cancer (LLABC) and their contribution to a pathological complete response (PCR) in the tumour following neoadjuvant chemotherapy (NAC): differential restoration of blood profiles by NAC and surgery
Cell phenotypes and functional status
% in the circulation of women with LLABCs (n = 25)
% In the circulation of HFDs (n = 10)
P value
NK granzyme B+/perforin+
43.41 ± 4.00
60.26 ± 7.00
0.003*
NK-NKG2D+
8.32 ± 3.50
4.00 ± 1.50
0.078