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Figure 3 | Journal of Translational Medicine

Figure 3

From: Natural killer (NK) cell profiles in blood and tumour in women with large and locally advanced breast cancer (LLABC) and their contribution to a pathological complete response (PCR) in the tumour following neoadjuvant chemotherapy (NAC): differential restoration of blood profiles by NAC and surgery

Figure 3

a Is an example (dot plot diagram) from a representative patient from Group 1 (pCR) and a HFD of FACS analysis of AbNs of NK (CD3−CD56dim) cells in the blood at baseline (prior to NAC), post NAC and post surgery. b Is an example (dot plot diagram) from a representative patient from Group 1 (pCR) and a HFD of FACS analysis of % NK (CD3−CD16+CD56dim) cells in the blood at baseline (prior to NAC), post NAC and post surgery. c Is an example (dot plot analysis) from a representative patient from Group 1 (pCR) and a HFD of FACS analysis of % of granzyme B+/perforin+ NK (CD3−CD16+CD56dim) cells in the blood at baseline (prior to NAC), post NAC and post surgery. d Is an example (histogram) from a representative patient from Group 1 (pCR) and a HFD of FACS analysis (dark histogram is control) of % of NK-NKG2D+ (CD3−CD16+CD56dim) cells at baseline (prior to NAC), post NAC and post surgery.

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