TY - JOUR AU - Mosesson, Y. AU - Yarden, Y. PY - 2004 DA - 2004// TI - Oncogenic growth factor receptors: implications for signal transduction therapy JO - Semin Cancer Biol VL - 14 UR - https://doi.org/10.1016/j.semcancer.2004.04.005 DO - 10.1016/j.semcancer.2004.04.005 ID - Mosesson2004 ER - TY - JOUR AU - Slamon, D. J. AU - Clark, G. M. AU - Wong, S. G. AU - Levin, W. J. AU - Ullrich, A. AU - McGuire, W. L. PY - 1987 DA - 1987// TI - Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene JO - Science VL - 235 UR - https://doi.org/10.1126/science.3798106 DO - 10.1126/science.3798106 ID - Slamon1987 ER - TY - JOUR AU - Bartlett, J. AU - Mallon, E. AU - Cooke, T. PY - 2003 DA - 2003// TI - The clinical evaluation of HER-2 status: which test to use? JO - J Pathol VL - 199 UR - https://doi.org/10.1002/path.1354 DO - 10.1002/path.1354 ID - Bartlett2003 ER - TY - JOUR AU - Gancberg, D. AU - Jarvinen, T. AU - Leo, A. AU - Rouas, G. AU - Cardoso, F. AU - Paesmans, M. PY - 2002 DA - 2002// TI - Evaluation of HER-2/NEU protein expression in breast cancer by immunohistochemistry: an interlaboratory study assessing the reproducibility of HER-2/NEU testing JO - Breast Cancer Res Treat VL - 74 UR - https://doi.org/10.1023/A:1016146130767 DO - 10.1023/A:1016146130767 ID - Gancberg2002 ER - TY - JOUR AU - Thomson, T. A. AU - Hayes, M. M. AU - Spinelli, J. J. AU - Hilland, E. AU - Sawrenko, C. AU - Phillips, D. PY - 2001 DA - 2001// TI - HER-2/neu in breast cancer: interobserver variability and performance of immunohistochemistry with four antibodies compared with fluorescent in situ hybridization JO - Mod Pathol VL - 14 UR - https://doi.org/10.1038/modpathol.3880440 DO - 10.1038/modpathol.3880440 ID - Thomson2001 ER - TY - JOUR AU - Gjerdrum, L. M. AU - Sorensen, B. S. AU - Kjeldsen, E. AU - Sorensen, F. B. AU - Nexo, E. AU - Hamilton-Dutoit, S. PY - 2004 DA - 2004// TI - Real-time quantitative PCR of microdissected paraffin-embedded breast carcinoma: an alternative method for HER-2/neu analysis JO - J Mol Diagn VL - 6 UR - https://doi.org/10.1016/S1525-1578(10)60490-4 DO - 10.1016/S1525-1578(10)60490-4 ID - Gjerdrum2004 ER - TY - JOUR AU - Koutras, A. K. AU - Kalogeras, K. T. AU - Dimopoulos, M. A. AU - Wirtz, R. M. AU - Dafni, U. AU - Briasoulis, E. PY - 2008 DA - 2008// TI - Evaluation of the prognostic and predictive value of HER family mRNA expression in high-risk early breast cancer: a Hellenic Cooperative Oncology Group (HeCOG) study JO - Br J Cancer VL - 99 UR - https://doi.org/10.1038/sj.bjc.6604769 DO - 10.1038/sj.bjc.6604769 ID - Koutras2008 ER - TY - JOUR AU - Gogas, H. AU - Dafni, U. AU - Karina, M. AU - Papadimitriou, C. AU - Batistatou, A. AU - Bobos, M. PY - 2012 DA - 2012// TI - Postoperative dose-dense sequential versus concomitant administration of epirubicin and paclitaxel in patients with node-positive breast cancer: 5-year results of the Hellenic Cooperative Oncology Group HE 10/00 phase III Trial JO - Breast Cancer Res Treat VL - 132 UR - https://doi.org/10.1007/s10549-011-1913-4 DO - 10.1007/s10549-011-1913-4 ID - Gogas2012 ER - TY - JOUR AU - Razis, E. AU - Bobos, M. AU - Kotoula, V. AU - Eleftheraki, A. G. AU - Kalofonos, H. P. AU - Pavlakis, K. PY - 2011 DA - 2011// TI - Evaluation of the association of PIK3CA mutations and PTEN loss with efficacy of trastuzumab therapy in metastatic breast cancer JO - Breast Cancer Res Treat VL - 128 UR - https://doi.org/10.1007/s10549-011-1572-5 DO - 10.1007/s10549-011-1572-5 ID - Razis2011 ER - TY - JOUR AU - McShane, L. M. AU - Altman, D. G. AU - Sauerbrei, W. AU - Taube, S. E. AU - Gion, M. AU - Clark, G. M. PY - 2006 DA - 2006// TI - REporting recommendations for tumor MARKer prognostic studies (REMARK) JO - Breast Cancer Res Treat VL - 100 UR - https://doi.org/10.1007/s10549-006-9242-8 DO - 10.1007/s10549-006-9242-8 ID - McShane2006 ER - TY - JOUR AU - Kononen, J. AU - Bubendorf, L. AU - Kallioniemi, A. AU - Barlund, M. AU - Schraml, P. AU - Leighton, S. PY - 1998 DA - 1998// TI - Tissue microarrays for high-throughput molecular profiling of tumor specimens JO - Nat Med VL - 4 UR - https://doi.org/10.1038/nm0798-844 DO - 10.1038/nm0798-844 ID - Kononen1998 ER - TY - JOUR AU - Skacel, M. AU - Skilton, B. AU - Pettay, J. D. AU - Tubbs, R. R. PY - 2002 DA - 2002// TI - Tissue microarrays: a powerful tool for high-throughput analysis of clinical specimens: a review of the method with validation data JO - Appl Immunohistochem Mol Morphol VL - 10 ID - Skacel2002 ER - TY - JOUR AU - Fountzilas, G. AU - Kourea, H. P. AU - Bobos, M. AU - Televantou, D. AU - Kotoula, V. AU - Papadimitriou, C. PY - 2011 DA - 2011// TI - Paclitaxel and bevacizumab as first line combined treatment in patients with metastatic breast cancer: the Hellenic Cooperative Oncology Group experience with biological marker evaluation JO - Anticancer Res VL - 31 ID - Fountzilas2011 ER - TY - JOUR AU - Schippinger, W. AU - Dandachi, N. AU - Regitnig, P. AU - Hofmann, G. AU - Balic, M. AU - Neumann, R. PY - 2007 DA - 2007// TI - The predictive value of EGFR and HER-2/neu in tumor tissue and serum for response to anthracycline-based neoadjuvant chemotherapy of breast cancer JO - Am J Clin Pathol VL - 128 UR - https://doi.org/10.1309/51KPD70348RP6XTE DO - 10.1309/51KPD70348RP6XTE ID - Schippinger2007 ER - TY - JOUR AU - Wolff, A. C. AU - Hammond, M. E. AU - Schwartz, J. N. AU - Hagerty, K. L. AU - Allred, D. C. AU - Cote, R. J. PY - 2007 DA - 2007// TI - American Society of Clinical Oncology/College of American Pathologists guideline recommendations for human epidermal growth factor receptor 2 testing in breast cancer JO - J Clin Oncol VL - 25 UR - https://doi.org/10.1200/JCO.2006.09.2775 DO - 10.1200/JCO.2006.09.2775 ID - Wolff2007 ER - TY - JOUR AU - Hammond, M. E. AU - Hayes, D. F. AU - Dowsett, M. AU - Allred, D. C. AU - Hagerty, K. L. AU - Badve, S. PY - 2010 DA - 2010// TI - American Society of Clinical Oncology/College Of American Pathologists guideline recommendations for immunohistochemical testing of estrogen and progesterone receptors in breast cancer JO - J Clin Oncol VL - 28 UR - https://doi.org/10.1200/JCO.2009.25.6529 DO - 10.1200/JCO.2009.25.6529 ID - Hammond2010 ER - TY - JOUR AU - Cheang, M. C. AU - Chia, S. K. AU - Voduc, D. AU - Gao, D. AU - Leung, S. AU - Snider, J. PY - 2009 DA - 2009// TI - Ki67 index, HER2 status, and prognosis of patients with luminal B breast cancer JO - J Natl Cancer Inst VL - 101 UR - https://doi.org/10.1093/jnci/djp082 DO - 10.1093/jnci/djp082 ID - Cheang2009 ER - TY - JOUR AU - Press, M. F. AU - Sauter, G. AU - Buyse, M. AU - Bernstein, L. AU - Guzman, R. AU - Santiago, A. PY - 2011 DA - 2011// TI - Alteration of topoisomerase II-alpha gene in human breast cancer: association with responsiveness to anthracycline-based chemotherapy JO - J Clin Oncol VL - 29 UR - https://doi.org/10.1200/JCO.2009.27.5644 DO - 10.1200/JCO.2009.27.5644 ID - Press2011 ER - TY - JOUR AU - Vanden Bempt, I. AU - Van Loo, P. AU - Drijkoningen, M. AU - Neven, P. AU - Smeets, A. AU - Christiaens, M. R. PY - 2008 DA - 2008// TI - Polysomy 17 in breast cancer: clinicopathologic significance and impact on HER-2 testing JO - J Clin Oncol VL - 26 UR - https://doi.org/10.1200/JCO.2007.13.4296 DO - 10.1200/JCO.2007.13.4296 ID - Vanden Bempt2008 ER - TY - JOUR AU - Sauter, G. AU - Lee, J. AU - Bartlett, J. M. AU - Slamon, D. J. AU - Press, M. F. PY - 2009 DA - 2009// TI - Guidelines for human epidermal growth factor receptor 2 testing: biologic and methodologic considerations JO - J Clin Oncol VL - 27 UR - https://doi.org/10.1200/JCO.2007.14.8197 DO - 10.1200/JCO.2007.14.8197 ID - Sauter2009 ER - TY - JOUR AU - Pentheroudakis, G. AU - Kotoula, V. AU - Eleftheraki, A. G. AU - Tsolaki, E. AU - Wirtz, R. M. AU - Kalogeras, K. T. PY - 2013 DA - 2013// TI - Prognostic significance of ESR1 gene amplification, mRNA/protein expression and functional profiles in high-risk early breast cancer: a translational study of the Hellenic Cooperative Oncology Group (HeCOG) JO - PLoS One VL - 8 UR - https://doi.org/10.1371/journal.pone.0070634 DO - 10.1371/journal.pone.0070634 ID - Pentheroudakis2013 ER - TY - JOUR AU - Ginestier, C. AU - Charafe-Jauffret, E. AU - Penault-Llorca, F. AU - Geneix, J. AU - Adelaide, J. AU - Chaffanet, M. PY - 2004 DA - 2004// TI - Comparative multi-methodological measurement of ERBB2 status in breast cancer JO - J Pathol VL - 202 UR - https://doi.org/10.1002/path.1523 DO - 10.1002/path.1523 ID - Ginestier2004 ER - TY - JOUR AU - Vinatzer, U. AU - Dampier, B. AU - Streubel, B. AU - Pacher, M. AU - Seewald, M. J. AU - Stratowa, C. PY - 2005 DA - 2005// TI - Expression of HER2 and the coamplified genes GRB7 and MLN64 in human breast cancer: quantitative real-time reverse transcription-PCR as a diagnostic alternative to immunohistochemistry and fluorescence in situ hybridization JO - Clin Cancer Res VL - 11 UR - https://doi.org/10.1158/1078-0432.CCR-05-0841 DO - 10.1158/1078-0432.CCR-05-0841 ID - Vinatzer2005 ER - TY - JOUR AU - Pawlowski, V. AU - Revillion, F. AU - Hebbar, M. AU - Hornez, L. AU - Peyrat, J. P. PY - 2000 DA - 2000// TI - Prognostic value of the type I growth factor receptors in a large series of human primary breast cancers quantified with a real-time reverse transcription-polymerase chain reaction assay JO - Clin Cancer Res VL - 6 ID - Pawlowski2000 ER - TY - JOUR AU - Witton, C. J. AU - Reeves, J. R. AU - Going, J. J. AU - Cooke, T. G. AU - Bartlett, J. M. PY - 2003 DA - 2003// TI - Expression of the HER1-4 family of receptor tyrosine kinases in breast cancer JO - J Pathol VL - 200 UR - https://doi.org/10.1002/path.1370 DO - 10.1002/path.1370 ID - Witton2003 ER - TY - JOUR AU - Tsutsui, S. AU - Ohno, S. AU - Murakami, S. AU - Hachitanda, Y. AU - Oda, S. PY - 2002 DA - 2002// TI - Prognostic value of epidermal growth factor receptor (EGFR) and its relationship to the estrogen receptor status in 1,029 patients with breast cancer JO - Breast Cancer Res Treat VL - 71 UR - https://doi.org/10.1023/A:1013397232011 DO - 10.1023/A:1013397232011 ID - Tsutsui2002 ER - TY - JOUR AU - Tzaida, O. AU - Gogas, H. AU - Dafni, U. AU - Kyroudi, A. AU - Papaspyrou, I. AU - Kyriakou, V. PY - 2007 DA - 2007// TI - Evaluation of the prognostic and predictive value of HER-1/EGFR in breast cancer patients participating in a randomized study with dose-dense sequential adjuvant chemotherapy JO - Oncology VL - 72 UR - https://doi.org/10.1159/000113148 DO - 10.1159/000113148 ID - Tzaida2007 ER - TY - JOUR AU - Bergqvist, J. AU - Ohd, J. F. AU - Smeds, J. AU - Klaar, S. AU - Isola, J. AU - Nordgren, H. PY - 2007 DA - 2007// TI - Quantitative real-time PCR analysis and microarray-based RNA expression of HER2 in relation to outcome JO - Ann Oncol VL - 18 UR - https://doi.org/10.1093/annonc/mdm059 DO - 10.1093/annonc/mdm059 ID - Bergqvist2007 ER - TY - JOUR AU - Henderson, I. C. AU - Berry, D. A. AU - Demetri, G. D. AU - Cirrincione, C. T. AU - Goldstein, L. J. AU - Martino, S. PY - 2003 DA - 2003// TI - Improved outcomes from adding sequential paclitaxel but not from escalating doxorubicin dose in an adjuvant chemotherapy regimen for patients with node-positive primary breast cancer JO - J Clin Oncol VL - 21 UR - https://doi.org/10.1200/JCO.2003.02.063 DO - 10.1200/JCO.2003.02.063 ID - Henderson2003 ER - TY - JOUR AU - Hayes, D. F. AU - Thor, A. D. AU - Dressler, L. G. AU - Weaver, D. AU - Edgerton, S. AU - Cowan, D. PY - 2007 DA - 2007// TI - HER2 and response to paclitaxel in node-positive breast cancer JO - N Engl J Med VL - 357 UR - https://doi.org/10.1056/NEJMoa071167 DO - 10.1056/NEJMoa071167 ID - Hayes2007 ER - TY - JOUR AU - Dhesy-Thind, B. AU - Pritchard, K. I. AU - Messersmith, H. AU - O’Malley, F. AU - Elavathil, L. AU - Trudeau, M. PY - 2008 DA - 2008// TI - HER2/neu in systemic therapy for women with breast cancer: a systematic review JO - Breast Cancer Res Treat VL - 109 UR - https://doi.org/10.1007/s10549-007-9656-y DO - 10.1007/s10549-007-9656-y ID - Dhesy-Thind2008 ER - TY - JOUR AU - Martin, M. AU - Pienkowski, T. AU - Mackey, J. AU - Pawlicki, M. AU - Guastalla, J. P. AU - Weaver, C. PY - 2005 DA - 2005// TI - Adjuvant docetaxel for node-positive breast cancer JO - N Engl J Med VL - 352 UR - https://doi.org/10.1056/NEJMoa043681 DO - 10.1056/NEJMoa043681 ID - Martin2005 ER - TY - JOUR AU - Kostopoulos, I. AU - Arapantoni-Dadioti, P. AU - Gogas, H. AU - Papadopoulos, S. AU - Malamou-Mitsi, V. AU - Scopa, C. D. PY - 2006 DA - 2006// TI - Evaluation of the prognostic value of HER-2 and VEGF in breast cancer patients participating in a randomized study with dose-dense sequential adjuvant chemotherapy JO - Breast Cancer Res Treat VL - 96 UR - https://doi.org/10.1007/s10549-005-9062-2 DO - 10.1007/s10549-005-9062-2 ID - Kostopoulos2006 ER - TY - JOUR AU - Amin, D. N. AU - Campbell, M. R. AU - Moasser, M. M. PY - 2010 DA - 2010// TI - The role of HER3, the unpretentious member of the HER family, in cancer biology and cancer therapeutics JO - Semin Cell Dev Biol VL - 21 UR - https://doi.org/10.1016/j.semcdb.2010.08.007 DO - 10.1016/j.semcdb.2010.08.007 ID - Amin2010 ER - TY - JOUR AU - Bieche, I. AU - Onody, P. AU - Tozlu, S. AU - Driouch, K. AU - Vidaud, M. AU - Lidereau, R. PY - 2003 DA - 2003// TI - Prognostic value of ERBB family mRNA expression in breast carcinomas JO - Int J Cancer VL - 106 UR - https://doi.org/10.1002/ijc.11273 DO - 10.1002/ijc.11273 ID - Bieche2003 ER - TY - JOUR AU - Sassen, A. AU - Rochon, J. AU - Wild, P. AU - Hartmann, A. AU - Hofstaedter, F. AU - Schwarz, S. PY - 2008 DA - 2008// TI - Cytogenetic analysis of HER1/EGFR, HER2, HER3 and HER4 in 278 breast cancer patients JO - Breast Cancer Res VL - 10 UR - https://doi.org/10.1186/bcr1843 DO - 10.1186/bcr1843 ID - Sassen2008 ER - TY - JOUR AU - Quinn, C. M. AU - Ostrowski, J. L. AU - Lane, S. A. AU - Loney, D. P. AU - Teasdale, J. AU - Benson, F. A. PY - 1994 DA - 1994// TI - c-erbB-3 protein expression in human breast cancer: comparison with other tumour variables and survival JO - Histopathology VL - 25 UR - https://doi.org/10.1111/j.1365-2559.1994.tb01324.x DO - 10.1111/j.1365-2559.1994.tb01324.x ID - Quinn1994 ER - TY - JOUR AU - Lee, Y. AU - Cho, S. AU - Seo, J. H. AU - Shin, B. K. AU - Kim, H. K. AU - Kim, I. PY - 2007 DA - 2007// TI - Correlated expression of erbB-3 with hormone receptor expression and favorable clinical outcome in invasive ductal carcinomas of the breast JO - Am J Clin Pathol VL - 128 UR - https://doi.org/10.1309/GA5VRFQFY5D0MVKD DO - 10.1309/GA5VRFQFY5D0MVKD ID - Lee2007 ER - TY - JOUR AU - Offterdinger, M. AU - Schofer, C. AU - Weipoltshammer, K. AU - Grunt, T. W. PY - 2002 DA - 2002// TI - c-erbB-3: a nuclear protein in mammary epithelial cells JO - J Cell Biol VL - 157 UR - https://doi.org/10.1083/jcb.200109033 DO - 10.1083/jcb.200109033 ID - Offterdinger2002 ER - TY - JOUR AU - Koutras, A. K. AU - Fountzilas, G. AU - Kalogeras, K. T. AU - Starakis, I. AU - Iconomou, G. AU - Kalofonos, H. P. PY - 2010 DA - 2010// TI - The upgraded role of HER3 and HER4 receptors in breast cancer JO - Crit Rev Oncol Hematol VL - 74 UR - https://doi.org/10.1016/j.critrevonc.2009.04.011 DO - 10.1016/j.critrevonc.2009.04.011 ID - Koutras2010 ER - TY - JOUR AU - Suo, Z. AU - Risberg, B. AU - Kalsson, M. G. AU - Willman, K. AU - Tierens, A. AU - Skovlund, E. PY - 2002 DA - 2002// TI - EGFR family expression in breast carcinomas. c-erbB-2 and c-erbB-4 receptors have different effects on survival JO - J Pathol VL - 196 UR - https://doi.org/10.1002/path.1003 DO - 10.1002/path.1003 ID - Suo2002 ER - TY - JOUR AU - Naresh, A. AU - Long, W. AU - Vidal, G. A. AU - Wimley, W. C. AU - Marrero, L. AU - Sartor, C. I. PY - 2006 DA - 2006// TI - The ERBB4/HER4 intracellular domain 4ICD is a BH3-only protein promoting apoptosis of breast cancer cells JO - Cancer Res VL - 66 UR - https://doi.org/10.1158/0008-5472.CAN-05-2368 DO - 10.1158/0008-5472.CAN-05-2368 ID - Naresh2006 ER - TY - JOUR AU - Sartor, C. I. AU - Zhou, H. AU - Kozlowska, E. AU - Guttridge, K. AU - Kawata, E. AU - Caskey, L. PY - 2001 DA - 2001// TI - Her4 mediates ligand-dependent antiproliferative and differentiation responses in human breast cancer cells JO - Mol Cell Biol VL - 21 UR - https://doi.org/10.1128/MCB.21.13.4265-4275.2001 DO - 10.1128/MCB.21.13.4265-4275.2001 ID - Sartor2001 ER -