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Table 3 Top 27 down-regulated genes in young patients with breast cancer

From: The expression of CXCL13 and its relation to unfavorable clinical characteristics in young breast cancer

NO. Gene_symbol Gene_name FC P
1 NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase) 0.37 2.3 × 10−3
2 GRIA2 Glutamate receptor, ionotropic, AMPA 2 0.45 1.5 × 10−2
3 C6orf211 Chromosome 6 open reading frame 211 0.49 9.9 × 10−3
4 PSD3 Pleckstrin and Sec7 domain containing 3 0.49 6.1 × 10−4
5 GFRA1 GDNF family receptor alpha 1 0.49 3.4 × 10−3
6 EVL Enah/Vasp-like 0.50 1.0 × 10−3
7 SCUBE2 Signal peptide, CUB domain, EGF-like 2 0.51 2.2 × 10−2
8 DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12 0.52 1.9 × 10−3
9 KCNE4 Potassium voltage-gated channel, Iskrelated family, member 4 0.52 7.5 × 10−3
10 ECM1 Extracellular matrix protein 1 0.52 1.8 × 10−3
11 TBC1D9 TBC1 domain family, member 9 (with GRAM domain) 0.53 4.6 × 10−4
12 CYP2B7P1 Cytochrome P450, family 2, subfamily B, polypeptide 7 pseudogene 1 0.53 7.3 × 10−3
13 ESR1 Estrogen receptor 1 0.54 8.3 × 10−8
14 CA12 Carbonic anhydrase XII 0.55 1.2 × 10−3
15 MYB V-myb myeloblastosis viral oncogene homolog (avian) 0.56 1.4 × 10−2
16 PLAT Plasminogen activator, tissue 0.59 2.7 × 10−2
17 PGR Progesterone receptor 0.59 1.6 × 10−2
18 CLGN Calmegin 0.60 2.5 × 10−3
19 SLC44A4 Solute carrier family 44, member 4 0.61 8.1 × 10−3
20 REEP1 Receptor accessory protein 1 0.62 9.6 × 10−4
21 AR Androgen receptor 0.64 9.7 × 10−4
22 F7 Coagulation factor VII (serum prothrombin conversion accelerator) 0.64 2.1 × 10−3
23 CCDC170 Coiled-coil domain containing 170 0.64 1.3 × 10−4
24 SELENBP1 Selenium binding protein 1 0.65 2.3 × 10−2
25 PRKAR2B Protein kinase, cAMP-dependent, regulatory, type II, beta 0.65 2.0 × 10−3
26 GLCE Glucuronic acid epimerase 0.66 2.0 × 10−4
27 RNASE4 Ribonuclease, RNase A family, 4 0.66 9.5 × 10−4
  1. Abbreviations: FC, Fold change