Table 2 Top 36 up-regulated genes in young patients with breast cancer
NO. | Gene_symbol | Gene_name | FC | P |
|---|---|---|---|---|
1 | KRT14 | Keratin 14 | 4.31 | 5.8 × 10−7 |
2 | GABRP | Gamma-aminobutyric acid (GABA) A receptor, pi | 2.82 | 7.2 × 10−6 |
3 | PROM1 | Prominin 1 | 2.76 | 2.6 × 10−4 |
4 | CXCL13 | Chemokine (C-X-C motif) ligand 13 | 2.64 | 8.2 × 10−4 |
5 | IGHM | Immunoglobulin heavy constant mu | 2.63 | 1.7 × 10−4 |
6 | IGLL3P | Immunoglobulin lambda-like polypeptide 3, pseudogene | 2.61 | 1.5 × 10−3 |
7 | MMP7 | Matrix metallopeptidase 7 (matriysin, uterine) | 2.52 | 2.3 × 10−4 |
8 | IGJ | Immunoglobulin J polypeptide | 2.40 | 8.0 × 10−4 |
9 | KRT17 | Keratin 17 | 2.37 | 7.4 × 10−7 |
10 | GUSBP11 | Glucuronidase, beta pseudogene 11 | 2.35 | 2.0 × 10−3 |
11 | KRT15 | Keratin 15 | 2.16 | 1.4 × 10−3 |
12 | KRT7 | Keratin 7 | 2.14 | 3.1 × 10−3 |
13 | TSPYL5 | TSPY-like 5 | 2.03 | 5.0 × 10−5 |
14 | IGKC | Immunoglobulin kappa constant | 1.97 | 2.4 × 10−3 |
15 | S100A2 | S100 calcium binding protein A2 | 1.91 | 2.1 × 10−4 |
16 | LDHB | Lactate dehydrogenase B | 1.85 | 6.4 × 10−4 |
17 | SFRP1 | Secreted frizzled-related protein 1 | 1.83 | 5.5 × 10−4 |
18 | KRT5 | Keratin 5 | 1.79 | 6.1 × 10−4 |
19 | CDH3 | Cadherin 3, type 1, P-cadherin (placental) | 1.78 | 9.9 × 10−6 |
20 | RND3 | Rho family GTPase 3 | 1.78 | 9.7 × 10−6 |
21 | SYNM | Synemin, intermediate filament protein | 1.76 | 1.8 × 10−4 |
22 | KIT | V-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog | 1.75 | 7.0 × 10−6 |
23 | KRT6B | Keratin 6B | 1.75 | 1.3 × 10−4 |
24 | MT1X | Metallothionein 1X | 1.74 | 1.8 × 10−3 |
25 | AMIGO2 | Adhesion molecule with Ig-like domain 2 | 1.65 | 2.1 × 10−3 |
26 | SLC6A14 | Solute carrier family 6 (amino acid transporter), member 14 | 1.63 | 4.3 × 10−4 |
27 | RGS2 | Regulator of G-protein signaling 2, 24 kDa | 1.61 | 9.3 × 10−4 |
28 | SRGN | Serglycin | 1.60 | 2.9 × 10−3 |
29 | DDIT4 | DNA-damage-inducible transcript 4 | 1.60 | 1.4 × 10−3 |
30 | NFIB | Nuclear factor I/B | 1.58 | 1.8 × 10−3 |
31 | DTX4 | Deltex homolog 4 (Drosophila) | 1.58 | 1.4 × 10−4 |
32 | CSDA | Cold shock domain protein A | 1.57 | 3.8 × 10−4 |
33 | GBP2 | Guanylate binding protein 2, interferon-inducible | 1.54 | 1.8 × 10−3 |
34 | ITM2A | Integral membrane protein 2A | 1.53 | 1.9 × 10−3 |
35 | PADI2 | Peptidyl arginine deiminase, type II | 1.52 | 1.4 × 10−4 |
36 | RBMS1 | RNA binding motif, single stranded interacting protein 1 | 1.52 | 3.2 × 10−4 |