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Table 1 Clinical characteristic by age

From: The expression of CXCL13 and its relation to unfavorable clinical characteristics in young breast cancer

Characteristic Patients with breast cancer P
Young (≤45 ys) Old (≥65 ys)
(n = 535) (n = 74)
No. % No. %
Age, years    ---
 Range 20–45 65–87  
 Median 40 69  
Pathology    0.001
 IDC-NOS 457 85.4 54 72.9  
 ILC 16 3.0 3 4.1  
 DCIS 35 6.5 3 4.1  
 Others* 27 5.1 14 18.9  
Tumor size, mm    0.463
 Range 5–150 8–100  
 Median 24 25  
Tumor grade    0.009
 1 44 8.2 14 18.9  
 2 302 56.5 38 51.3  
 3 121 22.6 11 14.9  
 Missing 68 12.7 11 14.9  
Lymph node status    0.035
 Positive 245 45.8 24 32.4  
 Negative 288 53.8 49 66.2  
 Missing 2 0.4 1 1.4  
ER status    0.041
 Positive 331 61.9 55 74.3  
 Negative 202 37.7 19 25.7  
 Missing 2 0.4 --- ---  
PR status    0.739
 Positive 349 65.2 47 63.5  
 Negative 184 34.4 27 36.5  
 Missing 2 0.4 --- ---  
HER2 status    0.068
 Negative, 0-1+ 291 54.4 49 66.2  
 Equivocal, 2+ 122 22.8 13 17.6  
 Positive, 3+ 119 22.2 12 16.2  
 Missing 3 0.6 --- ---  
TNM staging    0.762
 0 34 6.4 4 5.4  
 I 134 25.1 21 28.4  
 II 219 40.9 29 39.2  
 III 120 22.4 16 21.6  
 IV 8 1.5 1 1.3  
 Missing 20 3.7 3 4.1  
Subtypes    0.005
 Luminal A 53 9.9 18 24.3  
 Luminal B 269 50.3 36 48.7  
 HER2 69 12.9 10 13.5  
 Triple negative 80 14.9 6 8.1  
 Missing 64 12.0 4 5.4  
  1. Abbreviations: IDC-NOS, invasive ductal carcinoma, not otherwise specified; ILC, invasive lobular carcinoma; DCIS, ductal carcinoma in situ
  2. *Medullary carcinoma, mucinous carcinoma, tubular carcinoma, invasive papillary carcinoma and other special types of invasive carcinoma