Table 1 Clinical characteristic by age
Characteristic | Patients with breast cancer | P | |||
|---|---|---|---|---|---|
Young (≤45 ys) | Old (≥65 ys) | ||||
(n = 535) | (n = 74) | ||||
No. | % | No. | % | ||
Age, years | Â | Â | --- | ||
 Range | 20–45 | 65–87 |  | ||
 Median | 40 | 69 |  | ||
Pathology | Â | Â | 0.001 | ||
 IDC-NOS | 457 | 85.4 | 54 | 72.9 |  |
 ILC | 16 | 3.0 | 3 | 4.1 |  |
 DCIS | 35 | 6.5 | 3 | 4.1 |  |
 Others* | 27 | 5.1 | 14 | 18.9 |  |
Tumor size, mm | Â | Â | 0.463 | ||
 Range | 5–150 | 8–100 |  | ||
 Median | 24 | 25 |  | ||
Tumor grade | Â | Â | 0.009 | ||
 1 | 44 | 8.2 | 14 | 18.9 |  |
 2 | 302 | 56.5 | 38 | 51.3 |  |
 3 | 121 | 22.6 | 11 | 14.9 |  |
 Missing | 68 | 12.7 | 11 | 14.9 |  |
Lymph node status | Â | Â | 0.035 | ||
 Positive | 245 | 45.8 | 24 | 32.4 |  |
 Negative | 288 | 53.8 | 49 | 66.2 |  |
 Missing | 2 | 0.4 | 1 | 1.4 |  |
ER status | Â | Â | 0.041 | ||
 Positive | 331 | 61.9 | 55 | 74.3 |  |
 Negative | 202 | 37.7 | 19 | 25.7 |  |
 Missing | 2 | 0.4 | --- | --- |  |
PR status | Â | Â | 0.739 | ||
 Positive | 349 | 65.2 | 47 | 63.5 |  |
 Negative | 184 | 34.4 | 27 | 36.5 |  |
 Missing | 2 | 0.4 | --- | --- |  |
HER2 status | Â | Â | 0.068 | ||
 Negative, 0-1+ | 291 | 54.4 | 49 | 66.2 |  |
 Equivocal, 2+ | 122 | 22.8 | 13 | 17.6 |  |
 Positive, 3+ | 119 | 22.2 | 12 | 16.2 |  |
 Missing | 3 | 0.6 | --- | --- |  |
TNM staging | Â | Â | 0.762 | ||
 0 | 34 | 6.4 | 4 | 5.4 |  |
 I | 134 | 25.1 | 21 | 28.4 |  |
 II | 219 | 40.9 | 29 | 39.2 |  |
 III | 120 | 22.4 | 16 | 21.6 |  |
 IV | 8 | 1.5 | 1 | 1.3 |  |
 Missing | 20 | 3.7 | 3 | 4.1 |  |
Subtypes | Â | Â | 0.005 | ||
 Luminal A | 53 | 9.9 | 18 | 24.3 |  |
 Luminal B | 269 | 50.3 | 36 | 48.7 |  |
 HER2 | 69 | 12.9 | 10 | 13.5 |  |
 Triple negative | 80 | 14.9 | 6 | 8.1 |  |
 Missing | 64 | 12.0 | 4 | 5.4 |  |