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Fig. 8 | Journal of Translational Medicine

Fig. 8

From: Notch-1 knockdown suppresses proliferation, migration and metastasis of salivary adenoid cystic carcinoma cells

Fig. 8

Notch-1 knockdown inhibits the migratory capacity of salivary adenoid cystic carcinoma cells. Mouse xenografts bearing SACC cells were established as detailed in Materials and methods. Tissue sections were made of xenografts after 6 weeks and immunohistochemical staining was done using anti-Notch-1 antibodies (a). Photographs of gross metastatic lung nodules is shown in (b) and the mean number of lung metastatic nodules is shown in (c) *p 1, 3 < 0.01, p 2, 3 < 0.01. (1, ACC-M (NC); 2, ACC-M Mock (PC); 3, pLenR-Notch-1-shRNA1)

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