Fig. 7
Varying CAR-T cell stimulation conditions impacts the dynamics of the CARhi response. a-c 1 × 105 CD8+ CAR-T–cells were co-incubated with various target cell lines at 2:1 E:T ratio and monitored for a target cell counts, b number of CARhi T cells, and c CD25 expression among CARhi cells. d-e 2.5 × 105 CD8+ CAR-T cells were co-incubated with CD19+ K562 at various E:T ratios and monitored for d number of CARhi cells and e CD25 expression among CARhi cells. Average values of triplicates are shown with error bars indicating ± 1 s.d.