Fig. 6From: Identification and selective expansion of functionally superior T cells expressing chimeric antigen receptorsAntigen re-challenge results in CAR expression reduction. Sorted CD8+ CARhi and CARlo cells were assayed for EGFRt surface expression after 24Â h of co-incubation. A small fraction of CARhi cells becomes CARlo upon antigen re-challenge, while a significant reduction in CAR expression is observed among CARlo cells after stimulationBack to article page