Fig. 2

Human EnSCs transplantation increased animal weight and restored cyclicity in sterilized mice. a Weight of untreated mice did not increase over the study period. Mice of EnSCs-treated groups weighed significantly more compared with chemoablated mice from the 4th week onward (*P <0.01); however, there was no significant difference between untreated control and EnSCs-treated groups (P > 0.05). b The percentage of substages of diestrus (DE), proestrus (PE), estrus (E) and metestrus (ME) in different groups. Cyclicity was similar to normal animals 4 weeks after cell transplantation, whereas changes in untreated control animals were maintained at diestrus throughout the experiment. U, Untreated control; E, Chemoablated with EnSCs transplantation group, C, Chemoablated group