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Table 1 Clinicopathological factors and GDH expression in 104 colorectal cancers

From: Glutamate dehydrogenase is a novel prognostic marker and predicts metastases in colorectal cancer patients

Factor GDH high expression GDH low expression P -value
n = 56, n (%) n = 48, n (%)
Age      
<60 27 48.2 26 54.2 0.545
≥60 29 51.8 22 45.8  
Gender      
Male 34 60.7 27 56.2 0.645
Female 22 39.3 21 43.8  
Location      
Colon 33 58.9 32 66.7 0.416
Rectum 23 41.1 16 33.3  
Tumor size      
<3cm 24 42.9 30 62.5 0.046*
≥3cm 32 57.1 18 37.5  
CEA      
Normal 26 46.4 25 52.1 0.656
Elevated 30 53.6 23 47.9  
Grade of differentiation     
Well 11 19.6 14 29.2 0.296
Moderate 35 62.5 27 56.3  
Poor 10 17.9 7 14.5  
Depth of invasion      
T1 and T2 31 55.4 26 54.2 0.903
T3 and T4 25 44.6 22 45.8  
Tumor stage      
I and II 14 25 28 58.3 0.001*
III and IV 42 75 20 41.7  
Lymph node metastasis
Negative 20 35.7 33 68.8 0.001*
Positive 36 64.3 15 31.2  
Liver metastasis      
Negative 40 71.4 43 89.6 0.021*
Positive 16 28.6 5 10.4  
Venous invasion      
Negative 50 89.3 45 93.8 0.501
Positive 6 10.7 3 6.2  
Nervous invasion      
Negative 36 64.3 38 79.2 0.095
Positive 20 35.7 10 20.8