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Table 1 Clinicopathological factors and GDH expression in 104 colorectal cancers

From: Glutamate dehydrogenase is a novel prognostic marker and predicts metastases in colorectal cancer patients

Factor

GDH high expression

GDH low expression

P -value

n = 56, n (%)

n = 48, n (%)

Age

     

<60

27

48.2

26

54.2

0.545

≥60

29

51.8

22

45.8

 

Gender

     

Male

34

60.7

27

56.2

0.645

Female

22

39.3

21

43.8

 

Location

     

Colon

33

58.9

32

66.7

0.416

Rectum

23

41.1

16

33.3

 

Tumor size

     

<3cm

24

42.9

30

62.5

0.046*

≥3cm

32

57.1

18

37.5

 

CEA

     

Normal

26

46.4

25

52.1

0.656

Elevated

30

53.6

23

47.9

 

Grade of differentiation

    

Well

11

19.6

14

29.2

0.296

Moderate

35

62.5

27

56.3

 

Poor

10

17.9

7

14.5

 

Depth of invasion

     

T1 and T2

31

55.4

26

54.2

0.903

T3 and T4

25

44.6

22

45.8

 

Tumor stage

     

I and II

14

25

28

58.3

0.001*

III and IV

42

75

20

41.7

 

Lymph node metastasis

Negative

20

35.7

33

68.8

0.001*

Positive

36

64.3

15

31.2

 

Liver metastasis

     

Negative

40

71.4

43

89.6

0.021*

Positive

16

28.6

5

10.4

 

Venous invasion

     

Negative

50

89.3

45

93.8

0.501

Positive

6

10.7

3

6.2

 

Nervous invasion

     

Negative

36

64.3

38

79.2

0.095

Positive

20

35.7

10

20.8

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