From: Establishment of a patient-derived orthotopic osteosarcoma mouse model
Age & Gender | 17Â years, female |
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Primary disease | diagnosed April 2008 |
  - histopathology | osteoblastic osteosarcoma |
  - Tumor location | right femur epiphysis, no metastases |
  - Treatment | according to EURAMOS 1 06/2008 – 11/2009, abortion of chemotherapy after the third postoperative cycle by request of the patient and her parents |
Extraarticular tumor resection of the right femur (09.09.2008) and implantation of a Mutars-Endoprothesis (regression grade II according to Salzer-Kuntschik) | |
1. Relapse | diagnosed 24Â months after diagnose of primary disease |
  - histopathology |  - osteoblastic osteosarcoma |
  - Location |  - multifocal lesions in the right tibia, both lungs bilateral and the mediastinum |
  - treatment |  - no further treatment because of the significant reduced general conditions and by request of the patient and her parents |
Death of disease | 8Â weeks after diagnose of relapse |
Family history | - Oldest child of four children |
 - Youngest brother died because of an embryonal rhabdomyosarcoma in 2000 | |
 - Mother died because of a Mamma-Ca in 2006 | |
 - Father, one younger sister and one younger brother are healthy | |
 - Diagnostic concerning familiar tumor predisposition syndrome was declined |