Figure 5

Crosstalk between NFAT5 and WNT/CTNNB1-signaling in IBC pathogenesis. A-B: NFAT5 positivity and its subcellular distribution according to the CTNNB1 activation in IBC and nIBC TMA validation series, respectively. CTNNB1 inactive indicates negative and/or membrane staining; CTNNB1 active indicates cytoplasmic, nuclear and/or nuclear/cytoplasmic accumulation. Abbreviations: cytoplasmic (C), nuclear (N) and nuclear/cytoplasmic (N/C).