Skip to main content

Table 3 Cyclin D1 and p27 tumor expression in the pre-treatment setting

From: Statin-induced anti-proliferative effects via cyclin D1 and p27 in a window-of-opportunity breast cancer trial

Patients completed all study parts

n = 42

Cyclin D1 nuclear fraction (n = 30)

 

 Negative

2 (7%)

 Low (1-50%)

12 (40%)

 High (51-100%)

16 (53%)

Cyclin D1 nuclear intensity (n = 30)

 

 Negative

2 (7%)

 Weak

5 (12%)

 Moderate

14 (33%)

 Strong

9 (30%)

Cyclin D1 cytoplasmic intensity (n = 30)

 

 Negative

11(37%)

 Weak

14 (47%)

 Moderate

2 (7%)

 Strong

3 (10%)

p27 nuclear fraction (n = 33)

 

 Negative

0

 Low (1-50%)

8 (24%)

 High (51-100%)

25 (76%)

p27 nuclear intensity (n = 33)

 

 Negative

0

 Weak

3 (9%)

 Moderate

18 (55%)

 Strong

12 (36%)

p27 cytoplasmic intensity (n = 33)

 Negative

17 (52%)

 Weak

14 (42%)

 Moderate

2 (6%)

 Strong

0