Figure 1
From: BAP1 mutation is a frequent somatic event in peritoneal malignant mesothelioma
Copy number alterations in 9 peritoneal MM tumors. (A) The cumulative number of base pairs affected by losses (blue) or gains (red) in large segments (>1 Mb) is indicated for each tumor. The corresponding number of segments (Lost/Gained) is mentioned next to the sample ID. (B) Net Log Ratio (x axis) and B allele frequency (y axis) calculated across all 9 tumors for 369 genes located in the 5 recurrently lost cytobands. 3p21 (red genes) shows the strongest net loss (x axis) and net LoH (y axis). The data points corresponding to PBRM1 and BAP1 genes are labeled. (*) the BAP1 data point overlaps with other genes located in the same segment.