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Table 3 Summary of CAT parameters and conventional clinical coagulation tests

From: Endothelial glycocalyx shedding and vascular permeability in severely injured trauma patients

 

Normal COP (N = 11)

Low COP (N = 11)

p-value

Lag time (min)

3.83 (3.46, 4.83)

3.78 (3.33, 4.83)

0.77

ETP (nM*min)

1227 (1011, 1314)

1053 (1009, 1223)

0.53

Peak (nM)

325.4 (277.7, 352.2)

249.4 (177.4, 285.8)*

0.02

ttpeak (min)

5.7 (5.3, 6.7)

5.7 (5.3, 6.7)

0.97

INR

1.12 (1.07, 1.22)

1.19 (1.09, 1.59)

0.28

aPTT (s)

28.3 (26.5, 33.4)

32.8 (24.6, 43.1)

0.67

PT (s)

14.4 (13.9, 15.4)

15.1 (14.1, 18.9)

0.28

  1. Median and IQR values are reported for each group. Peak thrombin generation is significantly lower in the Low COP group, as denoted by the asterisk (*).