From: Endothelial glycocalyx shedding and vascular permeability in severely injured trauma patients
Overall (N = 22) | Normal COP (N = 11) | Low COP (N = 11) | p-value | |
---|---|---|---|---|
Age (yrs) | 44 (31, 54) | 46 (31, 56) | 41 (29, 51) | 0.74 |
Male, n (%) | 16 (73%) | 8 (73%) | 8 (73%) | 0.69 |
Penetrating, n (%) | 5 (23%) | 1 (9%) | 4 (36%) | 0.22 |
SBP (mmHg) | 122 (108, 140) | 136 (119, 151) | 119 (93, 123) | 0.09 |
DBP (mmHg) | 67 (54, 80) | 75 (59, 80) | 60 (51, 74) | 0.17 |
HR (bpm) | 99 (79, 116) | 98 (90, 116) | 99 (78, 126) | 0.95 |
RR (bpm) | 17 (15, 20) | 16 (0, 18) | 18 (15, 22) | 0.28 |
GCS | 9 (3, 15) | 8 (3, 15) | 10 (3, 14) | 0.73 |
ISS | 22 (13, 34) | 19 (9, 22) | 34 (17, 43)* | 0.02 |
pH | 7.27 (708, 7.35) | 7.35 (7.23, 7.42) | 7.19 (6.91, 7.31)* | 0.03 |
Base excess (mEq/L) | −2 (−3, 0) | −1 (−3, 0) | −3 (−10, 0) | 0.23 |
24 hr-total blood (U) | 5 (0, 28) | 2 (0, 6) | 28 (3, 41)* | 0.006 |
24 hr-total crystalloid (mL) | 2200 (1287, 4800) | 1710 (1049, 7100) | 2875 (1287, 4800) | 0.82 |
Length of stay (days) | 7 (2, 20) | 5 (2, 17) | 9 (2, 24) | 0.87 |
Mortality, n (%) | 8 (36%) | 3 (27%) | 5 (45%) | 0.37 |