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Table 2 The percentages and absolute values of NK cell subsets after cytokine in vitro treatment

From: Favorable in vitro effects of combined IL-12 and IL-18 treatment on NK cell cytotoxicity and CD25 receptor expression in metastatic melanoma patients

  

18 h in vitro treatment

   

Medium

IL-12

IL-18

IL-12 + IL-18

Controls (n = 26)

Percentage (%)

CD3 CD56 +

13.76 ± 1.75#

14.58 ± 2.67

13.92 ± 2.66

12.47 ± 2.14

CD3 CD56 dim+

12.72 ± 1.76

13.39 ± 2.64

12.04 ± 2.26

11.53 ± 2.13

CD3 CD56 bright+

1.06 ± 0.11

1.18 ± 0.15

1.07 ± 0.20

0.90 ± 0.12

Apsolute values (/μl)

CD3 CD56 +

261.53 ± 19.33

280.53 ± 29.33

255.28 ± 21.38

275.14 ± 23.33

CD3 CD56 dim+

250.87 ± 30.54

260.71 ± 32.55

249.39 ± 33.83

259.12 ± 35.22

CD3 CD56 bright+

19.63 ± 1.39

21.13 ± 0.19

18.87 ± 0.09

20.18 ± 1.01

Patients (n = 36)

Percentage (%)

CD3 CD56 +

16.61 ± 1.99

16.82 ± 2.11

17.70 ± 2.42

17.72 ± 2.31

CD3 CD56 dim+

15.56 ± 1.96

15.82 ± 2.10

16.63 ± 2.40

16.66 ± 2.29

CD3 CD56 bright+

1.05 ± 0.09

1.06 ± 0.08

1.07 ± 0.10

1.03 ± 0.12

Apsolute values (/μl)

CD3 CD56 +

328.32 ± 21.33

319.83 ± 28.33

319.83 ± 25.13

338.51 ± 23.33

CD3 CD56 dim+

305.13 ± 20.96

300.75 ± 39.73

321.27 ± 27.23

325.17 ± 27.71

CD3 CD56 bright+

22.87 ± 0.19

25.34 ± 0.09

26.13 ± 0.33

20.01 ± 0.10

  1. #Results are expressed as mean values ± SE. Absolute numbers were calculated by multiplying PBL number in the blood count with percentage for each subset obtained by flow cytometry.