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Table 2 The percentages and absolute values of NK cell subsets after cytokine in vitro treatment

From: Favorable in vitro effects of combined IL-12 and IL-18 treatment on NK cell cytotoxicity and CD25 receptor expression in metastatic melanoma patients

   18 h in vitro treatment
    Medium IL-12 IL-18 IL-12 + IL-18
Controls (n = 26) Percentage (%) CD3 − CD56 + 13.76 ± 1.75# 14.58 ± 2.67 13.92 ± 2.66 12.47 ± 2.14
CD3 − CD56 dim+ 12.72 ± 1.76 13.39 ± 2.64 12.04 ± 2.26 11.53 ± 2.13
CD3 − CD56 bright+ 1.06 ± 0.11 1.18 ± 0.15 1.07 ± 0.20 0.90 ± 0.12
Apsolute values (/μl) CD3 − CD56 + 261.53 ± 19.33 280.53 ± 29.33 255.28 ± 21.38 275.14 ± 23.33
CD3 − CD56 dim+ 250.87 ± 30.54 260.71 ± 32.55 249.39 ± 33.83 259.12 ± 35.22
CD3 − CD56 bright+ 19.63 ± 1.39 21.13 ± 0.19 18.87 ± 0.09 20.18 ± 1.01
Patients (n = 36) Percentage (%) CD3 − CD56 + 16.61 ± 1.99 16.82 ± 2.11 17.70 ± 2.42 17.72 ± 2.31
CD3 − CD56 dim+ 15.56 ± 1.96 15.82 ± 2.10 16.63 ± 2.40 16.66 ± 2.29
CD3 − CD56 bright+ 1.05 ± 0.09 1.06 ± 0.08 1.07 ± 0.10 1.03 ± 0.12
Apsolute values (/μl) CD3 − CD56 + 328.32 ± 21.33 319.83 ± 28.33 319.83 ± 25.13 338.51 ± 23.33
CD3 − CD56 dim+ 305.13 ± 20.96 300.75 ± 39.73 321.27 ± 27.23 325.17 ± 27.71
CD3 − CD56 bright+ 22.87 ± 0.19 25.34 ± 0.09 26.13 ± 0.33 20.01 ± 0.10
  1. #Results are expressed as mean values ± SE. Absolute numbers were calculated by multiplying PBL number in the blood count with percentage for each subset obtained by flow cytometry.
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Journal of Translational Medicine

ISSN: 1479-5876

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