Figure 5

Effects of andrographis injection on PLN weight in BALB/C mice. (a) WI and PLN weight of the treated groups. The measured WI and PLN weight show significant increases in the andrographis injection group compared with the 3% Tween 80 group, and no significant differences were observed between the 20% DMSO and 3% Tween 80 groups relative to the control group (saline group). The data are presented as the means ± SD from 10 mice per group. ^△P < 0.05 vs. the 3% Tween 80 group, ^★★P < 0.01 vs. the control group. (b) Histopathological findings in the PLNs. (A) Normal group, (B) Control group, (C) 3% Tween 80 group, (D) 20% DMSO group, (E) andrographis injection group, (F) DF group. H&E stain; magnification, 400×.