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Table 1 Baseline characteristics of primary and SLE-related AIHA patients

From: CXCL13, CCL4, and sTNFR as circulating inflammatory cytokine markers in primary and SLE-related autoimmune hemolytic anemia

 

Primary (n = 19)

SLE-related (n = 18)

p value

Age, years

57 ± 16

39 ± 20

0.004

Female gender

9 (47.4)

13 (72.2)

0.124

Hemoglobin, g/dl

6.9 ± 1.9

7.9 ± 2.6

0.199

Reticulocyte count,%

12.2 ± 8.6

6.8 ± 7.1

0.045§

Platelet count, ×109/L

166 ± 104

171 ± 101

0.874

Total bilirubin, mg/dl

3.1 ± 1.7

1.4 ± 1.4

0.002

Unconjugated bilirubin, mg/dl

1.9 ± 1.3

0.7 ± 0.7

0.002

Lactate dehydrogenase, U/L

622 (387-1154)

361 (265-498)

0.004

Complements

   

 C3, mg/dl

73.6 ± 31.8

56.5 ± 36.7

0.296

 C4, mg/dl

9.4 ± 5.5

7.2 ± 6.7

0.451

Direct antiglobulin test

   

 Anti-IgG (+)

19 (100)

18 (100)

1.000

 Anti-C3d (+)

15 (78.9)

17 (94.4)

0.370

Autoantibodies

   

 Antinuclear antibody (+)

13 (68.4)

17 (94.4)

0.110

 Anticardiolipin antibody (+)

2 (10.5)

9 (50.0)

0.009

 Indirect antiglobulin test, titer

8 (1-32)

2 (1-4)

0.169

Peripheral lymphocyte phenotype

   

 CD3+CD4+,%

36 ± 20

34 ± 9

0.804

 CD3+CD8+,%

33 ± 18

40 ± 11

0.294

 CD16+CD56+,%

7 ± 5

7 ± 4

0.984

 CD19+,%

21 ± 12

17 ± 7

0.365

  1. Data are presented as mean ± SD, as number (percentage), or as median (interquartile range).
  2. §p <0.05, p <0.01.