TY - JOUR AU - Geller, D. S. AU - Gorlick, R. PY - 2010 DA - 2010// TI - Osteosarcoma: a review of diagnosis, management, and treatment strategies JO - Clin Adv Hematol Oncol VL - 8 ID - Geller2010 ER - TY - JOUR AU - Marcove, R. C. AU - Mike, V. AU - Hajek, J. V. AU - Levin, A. G. AU - Hutter, R. V. PY - 1970 DA - 1970// TI - Osteogenic sarcoma under the age of twenty-one. A review of one hundred and forty-five operative cases JO - J Bone Joint Surg Am VL - 52 ID - Marcove1970 ER - TY - JOUR AU - Marina, N. AU - Gebhardt, M. AU - Teot, L. AU - Gorlick, R. PY - 2004 DA - 2004// TI - Biology and therapeutic advances for pediatric osteosarcoma JO - Oncologist VL - 9 UR - https://doi.org/10.1634/theoncologist.9-4-422 DO - 10.1634/theoncologist.9-4-422 ID - Marina2004 ER - TY - JOUR AU - Freedman, V. H. AU - Shin, S. I. PY - 1974 DA - 1974// TI - Cellular tumorigenicity in nude mice: correlation with cell growth in semi-solid medium JO - Cell VL - 3 UR - https://doi.org/10.1016/0092-8674(74)90050-6 DO - 10.1016/0092-8674(74)90050-6 ID - Freedman1974 ER - TY - JOUR AU - Gassmann, P. AU - Haier, J. PY - 2008 DA - 2008// TI - The tumor cell-host organ interface in the early onset of metastatic organ colonisation JO - Clin Exp Metastasis VL - 25 UR - https://doi.org/10.1007/s10585-007-9130-6 DO - 10.1007/s10585-007-9130-6 ID - Gassmann2008 ER - TY - JOUR AU - Paoli, P. AU - Giannoni, E. AU - Chiarugi, P. PY - 1833 DA - 1833// TI - Anoikis molecular pathways and its role in cancer progression JO - Biochim Biophys Acta VL - 2013 ID - Paoli1833 ER - TY - JOUR AU - Mori, S. AU - Chang, J. T. AU - Andrechek, E. R. AU - Matsumura, N. AU - Baba, T. AU - Yao, G. PY - 2009 DA - 2009// TI - Anchorage-independent cell growth signature identifies tumors with metastatic potential JO - Oncogene VL - 28 UR - https://doi.org/10.1038/onc.2009.139 DO - 10.1038/onc.2009.139 ID - Mori2009 ER - TY - JOUR AU - Douma, S. AU - Laar, T. AU - Zevenhoven, J. AU - Meuwissen, R. AU - Garderen, E. AU - Peeper, D. S. PY - 2004 DA - 2004// TI - Suppression of anoikis and induction of metastasis by the neurotrophic receptor TrkB JO - Nature VL - 430 UR - https://doi.org/10.1038/nature02765 DO - 10.1038/nature02765 ID - Douma2004 ER - TY - JOUR AU - Chiarugi, P. AU - Giannoni, E. PY - 2008 DA - 2008// TI - Anoikis: a necessary death program for anchorage-dependent cells JO - Biochem Pharmacol VL - 76 UR - https://doi.org/10.1016/j.bcp.2008.07.023 DO - 10.1016/j.bcp.2008.07.023 ID - Chiarugi2008 ER - TY - JOUR AU - Simpson, C. D. AU - Anyiwe, K. AU - Schimmer, A. D. PY - 2008 DA - 2008// TI - Anoikis resistance and tumor metastasis JO - Cancer Lett VL - 272 UR - https://doi.org/10.1016/j.canlet.2008.05.029 DO - 10.1016/j.canlet.2008.05.029 ID - Simpson2008 ER - TY - JOUR AU - Reddig, P. J. AU - Juliano, R. L. PY - 2005 DA - 2005// TI - Clinging to life: cell to matrix adhesion and cell survival JO - Cancer Metastasis Rev VL - 24 UR - https://doi.org/10.1007/s10555-005-5134-3 DO - 10.1007/s10555-005-5134-3 ID - Reddig2005 ER - TY - JOUR AU - Tang, Q. L. AU - Zhao, Z. Q. AU - Li, J. C. AU - Liang, Y. AU - Yin, J. Q. AU - Zou, C. Y. PY - 2011 DA - 2011// TI - Salinomycin inhibits osteosarcoma by targeting its tumor stem cells JO - Cancer Lett VL - 311 UR - https://doi.org/10.1016/j.canlet.2011.07.016 DO - 10.1016/j.canlet.2011.07.016 ID - Tang2011 ER - TY - JOUR AU - Martins-Neves, S. R. AU - Lopes, A. O. AU - do Carmo, A. AU - Paiva, A. A. AU - Simoes, P. C. AU - Abrunhosa, A. J. PY - 2012 DA - 2012// TI - Therapeutic implications of an enriched cancer stem-like cell population in a human osteosarcoma cell line JO - BMC Cancer VL - 12 UR - https://doi.org/10.1186/1471-2407-12-139 DO - 10.1186/1471-2407-12-139 ID - Martins-Neves2012 ER - TY - JOUR AU - Zhang, H. AU - Wu, H. AU - Zheng, J. AU - Yu, P. AU - Xu, L. AU - Jiang, P. PY - 2013 DA - 2013// TI - Transforming growth factor beta1 signal is crucial for dedifferentiation of cancer cells to cancer stem cells in osteosarcoma JO - Stem Cells VL - 31 UR - https://doi.org/10.1002/stem.1298 DO - 10.1002/stem.1298 ID - Zhang2013 ER - TY - JOUR AU - Fujii, H. AU - Honoki, K. AU - Tsujiuchi, T. AU - Kido, A. AU - Yoshitani, K. AU - Takakura, Y. PY - 2009 DA - 2009// TI - Sphere-forming stem-like cell populations with drug resistance in human sarcoma cell lines JO - Int J Oncol VL - 34 ID - Fujii2009 ER - TY - JOUR AU - Gibbs, C. P. AU - Kukekov, V. G. AU - Reith, J. D. AU - Tchigrinova, O. AU - Suslov, O. N. AU - Scott, E. W. PY - 2005 DA - 2005// TI - Stem-like cells in bone sarcomas: implications for tumorigenesis JO - Neoplasia VL - 7 UR - https://doi.org/10.1593/neo.05394 DO - 10.1593/neo.05394 ID - Gibbs2005 ER - TY - JOUR AU - Tsai, L. L. AU - Hu, F. W. AU - Lee, S. S. AU - Yu, C. H. AU - Yu, C. C. AU - Chang, Y. C. PY - 2014 DA - 2014// TI - Oct4 mediates tumor initiating properties in oral squamous cell carcinomas through the regulation of epithelial-mesenchymal transition JO - PLoS One VL - 9 UR - https://doi.org/10.1371/journal.pone.0087207 DO - 10.1371/journal.pone.0087207 ID - Tsai2014 ER - TY - JOUR AU - Guo, P. AU - Gao, A. AU - Zhang, G. AU - Han, H. AU - Zhou, Q. PY - 2013 DA - 2013// TI - Decoding the knots of initiation of oncogenic epithelial-mesenchymal transition in tumor progression JO - Curr Cancer Drug Targets VL - 13 UR - https://doi.org/10.2174/15680096113136660105 DO - 10.2174/15680096113136660105 ID - Guo2013 ER - TY - BOOK AU - Team, R. C. PY - 2013 DA - 2013// TI - R: A Language and environment for statistical computing PB - Vienna, Austria CY - R Foundation for Statistical Computing ID - Team2013 ER - TY - JOUR AU - Livak, K. J. AU - Schmittgen, T. D. PY - 2001 DA - 2001// TI - Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method JO - Methods VL - 25 UR - https://doi.org/10.1006/meth.2001.1262 DO - 10.1006/meth.2001.1262 ID - Livak2001 ER - TY - JOUR AU - Benjamini, Y. AU - Hochberg, Y. PY - 1995 DA - 1995// TI - Controlling the false discovery rate: a practical and powerful approach to multiple testing JO - J Royal Stat Soc VL - 57 ID - Benjamini1995 ER - TY - JOUR AU - Diaz-Montero, C. M. AU - McIntyre, B. W. PY - 2003 DA - 2003// TI - Acquisition of anoikis resistance in human osteosarcoma cells JO - Eur J Cancer VL - 39 UR - https://doi.org/10.1016/S0959-8049(03)00575-6 DO - 10.1016/S0959-8049(03)00575-6 ID - Diaz-Montero2003 ER - TY - JOUR AU - Cho, S. H. AU - Ahn, A. K. AU - Bhargava, P. AU - Lee, C. H. AU - Eischen, C. M. AU - McGuinness, O. PY - 2011 DA - 2011// TI - Glycolytic rate and lymphomagenesis depend on PARP14, an ADP ribosyltransferase of the B aggressive lymphoma (BAL) family JO - Proc Natl Acad Sci U S A VL - 108 UR - https://doi.org/10.1073/pnas.1017082108 DO - 10.1073/pnas.1017082108 ID - Cho2011 ER - TY - JOUR AU - Nunes-Xavier, C. E. AU - Elson, A. AU - Pulido, R. PY - 2012 DA - 2012// TI - Epidermal growth factor receptor (EGFR)-mediated positive feedback of protein-tyrosine phosphatase epsilon (PTPepsilon) on ERK1/2 and AKT protein pathways is required for survival of human breast cancer cells JO - J Biol Chem VL - 287 UR - https://doi.org/10.1074/jbc.M111.293928 DO - 10.1074/jbc.M111.293928 ID - Nunes-Xavier2012 ER - TY - JOUR AU - Pei, X. H. AU - Lv, X. Q. AU - Li, H. X. PY - 2014 DA - 2014// TI - Sox5 induces epithelial to mesenchymal transition by transactivation of Twist1 JO - Biochem Biophys Res Commun VL - 446 UR - https://doi.org/10.1016/j.bbrc.2014.02.109 DO - 10.1016/j.bbrc.2014.02.109 ID - Pei2014 ER - TY - JOUR AU - Ozaki, T. AU - Sugimoto, H. AU - Nakamura, M. AU - Hiraoka, K. AU - Yoda, H. AU - Sang, M. PY - 2015 DA - 2015// TI - Runt-related transcription factor 2 attenuates the transcriptional activity as well as DNA damage-mediated induction of pro-apoptotic TAp73 to regulate chemosensitivity JO - FEBS J VL - 282 UR - https://doi.org/10.1111/febs.13108 DO - 10.1111/febs.13108 ID - Ozaki2015 ER - TY - JOUR AU - Barton, C. A. AU - Gloss, B. S. AU - Qu, W. AU - Statham, A. L. AU - Hacker, N. F. AU - Sutherland, R. L. PY - 2010 DA - 2010// TI - Collagen and calcium-binding EGF domains 1 is frequently inactivated in ovarian cancer by aberrant promoter hypermethylation and modulates cell migration and survival JO - Br J Cancer VL - 102 UR - https://doi.org/10.1038/sj.bjc.6605429 DO - 10.1038/sj.bjc.6605429 ID - Barton2010 ER - TY - JOUR AU - Jiang, C. G. AU - Lv, L. AU - Liu, F. R. AU - Wang, Z. N. AU - Liu, F. N. AU - Li, Y. S. PY - 2011 DA - 2011// TI - Downregulation of connective tissue growth factor inhibits the growth and invasion of gastric cancer cells and attenuates peritoneal dissemination JO - Mol Cancer VL - 10 UR - https://doi.org/10.1186/1476-4598-10-122 DO - 10.1186/1476-4598-10-122 ID - Jiang2011 ER - TY - JOUR AU - Marshall, G. M. AU - Gherardi, S. AU - Xu, N. AU - Neiron, Z. AU - Trahair, T. AU - Scarlett, C. J. PY - 2010 DA - 2010// TI - Transcriptional upregulation of histone deacetylase 2 promotes Myc-induced oncogenic effects JO - Oncogene VL - 29 UR - https://doi.org/10.1038/onc.2010.332 DO - 10.1038/onc.2010.332 ID - Marshall2010 ER - TY - JOUR AU - Kurland, J. F. AU - Tansey, W. P. PY - 2008 DA - 2008// TI - Myc-mediated transcriptional repression by recruitment of histone deacetylase JO - Cancer Res VL - 68 UR - https://doi.org/10.1158/0008-5472.CAN-07-6552 DO - 10.1158/0008-5472.CAN-07-6552 ID - Kurland2008 ER - TY - JOUR AU - Zappasodi, R. AU - Cavane, A. AU - Iorio, M. V. AU - Tortoreto, M. AU - Guarnotta, C. AU - Ruggiero, G. PY - 2014 DA - 2014// TI - Pleiotropic antitumor effects of the pan-HDAC inhibitor ITF2357 against c-Myc-overexpressing human B-cell non-Hodgkin lymphomas JO - Int J Cancer VL - 135 UR - https://doi.org/10.1002/ijc.28852 DO - 10.1002/ijc.28852 ID - Zappasodi2014 ER - TY - JOUR AU - Song, D. AU - Ni, J. AU - Xie, H. AU - Ding, M. AU - Wang, J. PY - 2014 DA - 2014// TI - DNA demethylation in the PTEN gene promoter induced by 5-azacytidine activates PTEN expression in the MG-63 human osteosarcoma cell line JO - Exp Ther Med VL - 7 ID - Song2014 ER - TY - JOUR AU - Zhang, H. AU - Zhou, W. C. AU - Li, X. AU - Meng, W. B. AU - Zhang, L. AU - Zhu, X. L. PY - 2014 DA - 2014// TI - 5-Azacytidine suppresses the proliferation of pancreatic cancer cells by inhibiting the Wnt/beta-catenin signaling pathway JO - Genet Mol Res VL - 13 UR - https://doi.org/10.4238/2014.July.4.22 DO - 10.4238/2014.July.4.22 ID - Zhang2014 ER - TY - JOUR AU - Thayanithy, V. AU - Park, C. AU - Sarver, A. L. AU - Kartha, R. V. AU - Korpela, D. M. AU - Graef, A. J. PY - 2012 DA - 2012// TI - Combinatorial treatment of DNA and chromatin-modifying drugs cause cell death in human and canine osteosarcoma cell lines JO - PLoS One VL - 7 UR - https://doi.org/10.1371/journal.pone.0043720 DO - 10.1371/journal.pone.0043720 ID - Thayanithy2012 ER - TY - JOUR AU - Oronsky, B. AU - Oronsky, N. AU - Scicinski, J. AU - Fanger, G. AU - Lybeck, M. AU - Reid, T. PY - 2014 DA - 2014// TI - Rewriting the epigenetic code for tumor resensitization: a review JO - Transl Oncol VL - 7 UR - https://doi.org/10.1016/j.tranon.2014.08.003 DO - 10.1016/j.tranon.2014.08.003 ID - Oronsky2014 ER - TY - JOUR AU - Ma, Y. AU - Ren, Y. AU - Han, E. Q. AU - Li, H. AU - Chen, D. AU - Jacobs, J. J. PY - 2013 DA - 2013// TI - Inhibition of the Wnt-beta-catenin and Notch signaling pathways sensitizes osteosarcoma cells to chemotherapy JO - Biochem Biophys Res Commun VL - 431 UR - https://doi.org/10.1016/j.bbrc.2012.12.118 DO - 10.1016/j.bbrc.2012.12.118 ID - Ma2013 ER - TY - JOUR AU - Scholten, D. J. AU - Timmer, C. M. AU - Peacock, J. D. AU - Pelle, D. W. AU - Williams, B. O. AU - Steensma, M. R. PY - 2014 DA - 2014// TI - Down regulation of Wnt signaling mitigates hypoxia-induced chemoresistance in human osteosarcoma cells JO - PLoS One VL - 9 UR - https://doi.org/10.1371/journal.pone.0111431 DO - 10.1371/journal.pone.0111431 ID - Scholten2014 ER - TY - JOUR AU - Gan, L. AU - Liu, P. AU - Lu, H. AU - Chen, S. AU - Yang, J. AU - McCarthy, J. B. PY - 2009 DA - 2009// TI - Cyclin D1 promotes anchorage-independent cell survival by inhibiting FOXO-mediated anoikis JO - Cell Death Differ VL - 16 UR - https://doi.org/10.1038/cdd.2009.86 DO - 10.1038/cdd.2009.86 ID - Gan2009 ER - TY - JOUR AU - Carduner, L. AU - Picot, C. R. AU - Leroy-Dudal, J. AU - Blay, L. AU - Kellouche, S. AU - Carreiras, F. PY - 2014 DA - 2014// TI - Cell cycle arrest or survival signaling through alphav integrins, activation of PKC and ERK1/2 lead to anoikis resistance of ovarian cancer spheroids JO - Exp Cell Res VL - 320 UR - https://doi.org/10.1016/j.yexcr.2013.11.011 DO - 10.1016/j.yexcr.2013.11.011 ID - Carduner2014 ER - TY - JOUR AU - Basu-Roy, U. AU - Seo, E. AU - Ramanathapuram, L. AU - Rapp, T. B. AU - Perry, J. A. AU - Orkin, S. H. PY - 2012 DA - 2012// TI - Sox2 maintains self renewal of tumor-initiating cells in osteosarcomas JO - Oncogene VL - 31 UR - https://doi.org/10.1038/onc.2011.405 DO - 10.1038/onc.2011.405 ID - Basu-Roy2012 ER - TY - JOUR AU - Lee, S. H. AU - Oh, S. Y. AU - Do, S. I. AU - Lee, H. J. AU - Kang, H. J. AU - Rho, Y. S. PY - 2014 DA - 2014// TI - SOX2 regulates self-renewal and tumorigenicity of stem-like cells of head and neck squamous cell carcinoma JO - Br J Cancer VL - 111 UR - https://doi.org/10.1038/bjc.2014.528 DO - 10.1038/bjc.2014.528 ID - Lee2014 ER - TY - JOUR AU - Rubin, E. M. AU - Guo, Y. AU - Tu, K. AU - Xie, J. AU - Zi, X. AU - Hoang, B. H. PY - 2010 DA - 2010// TI - Wnt inhibitory factor 1 decreases tumorigenesis and metastasis in osteosarcoma JO - Mol Cancer Ther VL - 9 UR - https://doi.org/10.1158/1535-7163.MCT-09-0147 DO - 10.1158/1535-7163.MCT-09-0147 ID - Rubin2010 ER - TY - JOUR AU - Han, G. AU - Wang, Y. AU - Bi, W. PY - 2012 DA - 2012// TI - C-Myc overexpression promotes osteosarcoma cell invasion via activation of MEK-ERK pathway JO - Oncol Res VL - 20 UR - https://doi.org/10.3727/096504012X13522227232237 DO - 10.3727/096504012X13522227232237 ID - Han2012 ER - TY - JOUR AU - Shimizu, T. AU - Ishikawa, T. AU - Sugihara, E. AU - Kuninaka, S. AU - Miyamoto, T. AU - Mabuchi, Y. PY - 2010 DA - 2010// TI - c-MYC overexpression with loss of Ink4a/Arf transforms bone marrow stromal cells into osteosarcoma accompanied by loss of adipogenesis JO - Oncogene VL - 29 UR - https://doi.org/10.1038/onc.2010.312 DO - 10.1038/onc.2010.312 ID - Shimizu2010 ER - TY - JOUR AU - Pyndiah, S. AU - Tanida, S. AU - Ahmed, K. M. AU - Cassimere, E. K. AU - Choe, C. AU - Sakamuro, D. PY - 2011 DA - 2011// TI - c-MYC suppresses BIN1 to release poly(ADP-ribose) polymerase 1: a mechanism by which cancer cells acquire cisplatin resistance JO - Sci Signal VL - 4 UR - https://doi.org/10.1126/scisignal.2001556 DO - 10.1126/scisignal.2001556 ID - Pyndiah2011 ER - TY - JOUR AU - Ozaki, T. AU - Wu, D. AU - Sugimoto, H. AU - Nagase, H. AU - Nakagawara, A. PY - 2013 DA - 2013// TI - Runt-related transcription factor 2 (RUNX2) inhibits p53-dependent apoptosis through the collaboration with HDAC6 in response to DNA damage JO - Cell Death Dis VL - 4 UR - https://doi.org/10.1038/cddis.2013.127 DO - 10.1038/cddis.2013.127 ID - Ozaki2013 ER - TY - JOUR AU - Lucero, C. M. AU - Vega, O. A. AU - Osorio, M. M. AU - Tapia, J. C. AU - Antonelli, M. AU - Stein, G. S. PY - 2013 DA - 2013// TI - The cancer-related transcription factor Runx2 modulates cell proliferation in human osteosarcoma cell lines JO - J Cell Physiol VL - 228 UR - https://doi.org/10.1002/jcp.24218 DO - 10.1002/jcp.24218 ID - Lucero2013 ER - TY - JOUR AU - Ozaki, T. AU - Sugimoto, H. AU - Nakamura, M. AU - Hiraoka, K. AU - Yoda, H. AU - Sang, M. PY - 2015 DA - 2015// TI - Runt-related transcription factor 2 attenuates the transcriptional activity as well as DNA damage-mediated induction of pro-apoptotic TAp73 to regulate chemosensitivity JO - FEBS J VL - 282 UR - https://doi.org/10.1111/febs.13108 DO - 10.1111/febs.13108 ID - Ozaki2015 ER -