Let-7a inhibits migration, invasion and epithelial-mesenchymal transition by targeting HMGA2 in nasopharyngeal carcinoma

Table 1 Correlation between the clinicopathologic characteristics and expression of let-7a and HMGA2 in nasopharyngeal carcinoma

Characteristics	n	Let-7a		p	HMGA2		p
Characteristics	n	High, n(%)	Low, n(%)	p	High, n(%)	Low, n(%)	p
Gender
Male	28	14(50.0)	14(50.0)	1.000	12(42.9)	16(57.1)	0.063
Female	20	10(50.0)	10(50.0)	1.000	14(70.0)	6(30.0)	0.063
Age(y)
≥50	24	11(45.8)	13(54.2)	0.564	10(41.7)	14(58.3)	0.082
<50	24	13(54.2)	11(45.8)	0.564	16(66.7)	8(33.3)	0.082
Clinical stage
I-II	16	12(75.0)	4(25.0)	0.014	5(31.2)	11(68.8)	0.024
III-IV	32	12(37.5)	20(62.5)	0.014	21(65.6)	11(34.4)	0.024
T classification
T1-T2	21	15(71.4)	6(28.6)	0.009	9(42.9)	12(57.1)	0.165
T3-T4	27	9(33.3)	18(66.7)	0.009	17(63.0)	10(37.0)	0.165
N classification
N0-N1	19	13(68.4)	6(31.6)	0.039	5(26.3)	14(73.7)	0.002
N2-N3	29	11(37.9)	18(62.1)	0.039	21(72.4)	8(27.6)	0.002
Distant metastasis
No	44	24(54.5)	20(45.5)	0.117	23(52.3)	21(47.7)	0.727
Yes	4	0(0)	4(100)	0.117	3(75.0)	1(25.0)	0.727

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