Figure 5

Knockdown of HMGA2 suppressed NPC cells migration and invasion. (A) The growth curves determined by MTT assay showed that knockdown of HMGA2 had no effect on NPC cells growth. (B) Down-regulated HMGA2 expression dramatically decreased the ability of CNE-2 and 5-8F cells migration in vitro. (C) Suppressed HMGA2 expression inhibited invasiveness of CNE-2 and 5-8F cells. The results were expressed as fold change relative to the corresponding blank control. Data is presented as the mean ± SD. *, P < 0.001 compared with control.