Figure 1

Effect of the six compounds on HIV-1 replication (left panel X4, right panel R5) measured by the p24 assay on day 7 culture supernatants. Infections were carried out in triplicate cultures in complete medium plus 10% of heat-inactivated FCS. Data are reported as percent of control which are PBMC in the absence of any compound, but pre-incubated with DMSO at 0.2%, corresponding to the concentration present in 30 μM of the compound. Values refer to mean ± standard deviation (SD) of 4 independent experiments each with triplicate cultures.