Table 1 4H11-28z/fIL-12/EFGRt T cell dose escalation
Cohort | Dose level | Cyclophosphamide dose | 4H11-28z/fIL-12/EFGRt T cell dose | Number of patients |
|---|---|---|---|---|
-I | −1 | None | 1 × 105 cells/kg | 3-6 patients |
I | 1 | None | 3 × 105 cells/kg | 3-6 patients |
II | 1 | 750 mg/m2 | 3 × 105 cells/kg | 3-6 patients |
III | 2 | 750 mg/m2 | 1 × 106 cells/kg | 3-6 patients |
IV | 3 | 750 mg/m2 | 3 × 106 cells/kg | 3-6 patients |
V | 4 | 750 mg/m2 | 1 × 107 cells/kg | 3-6 patients |