Figure 3
From: Natural humoral immune response to ribosomal P0 protein in colorectal cancer patients
Expression of the C-22 P0 epitope in normal mucosa and colorectal cancer. Panel A. Immunohistochemical detection of the C-22 P0 epitope by MAb 2B2. Panel B. Intensity of the C-22 P0 epitope expression in colorectal tumors and in the adjacent normal mucosa. Bar graph shows a semiquantitative evaluation of the C-22 P0 epitope expression in colorectal tumors and the adjacent normal mucosa (p < 0.001). Panel C. Immunohistochemical detection of CD3+ T lymphocytes and CD20+ B lymphocytes in a colon adenocarcinoma from a patient positive for anti-P0 antibodies (40x).