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Figure 5 | Journal of Translational Medicine

Figure 5

From: Focused ultrasound-induced blood–brain barrier opening to enhance interleukin-12 delivery for brain tumor immunotherapy: a preclinical feasibility study

Figure 5

T lymphocyte population ratio and IHC histological confirmation. (A-C) T lymphocyte population ratio between CD3+/CD8+ (CTL) and CD4+/CD25+ (Treg) among different experimental groups in spleen (A), in MLN (B), and in brain tumor (C). (n = 12 per group) (D-K) Immunohistological chemistry (IHC) staining to show specific T lymphocyte distribution among the experimental groups ((D-G): Cytotoxic T lymphocytes; Regulatory T lymphocytes; n = 3 per group).

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