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Table 2 Glomerular filtration rate (GFR), Urinary albumin excretion rate (UAER), glycemic control and blood pressure at baseline and follow-up according to genotype

From: The PPARγ2 Pro12Ala variant is protective against progression of nephropathy in people with type 2 diabetes

 

Pro/Pro

ProAla

 

Baseline

Follow-up

Baseline

Follow-up

UAER (μg/mg)

17.1 (11.3-37.9)

24.5 (13.8-49.9)*

15.2 (9.4-26.3)

18.9 (11.9-30.7)

GFR (ml/min/ 1.73 m2)

82.8 ± 14.5

80.3 ± 17.3*

85.3. ±13.4

85.2 ± 13#

HbA1c (%)

7.0 ± 1.5

7.1 ± 1.4

6.9 ± 0.9

7.1 ± 0.8

PAS (mmHg)

135.3 ± 18.6

138.4 ± 22.5

133.0 ± 27.6

138.6 ± 23.1

PAD (mmHg)

78.4 ± 8.3

78.3 ± 10

78.7 ± 15.9

79.1 ± 12.6

  1. *p < 0.05 vs baseline; # p < 0.05 vs Pro/Pro genotype.