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Table 1 Characteristics of the study population according to the Pro12Ala genotype

From: The PPARγ2 Pro12Ala variant is protective against progression of nephropathy in people with type 2 diabetes

 

Pro/Pro (N =212)

ProAla (N = 44)

Males (%)

119 (56.1)

23 (52.3)

Age (years)

60.9 ± 4.1

60.3 ± 5.7

BMI (Kg/m2)

29.4 ± 4.0

29.6 ± 4.5

HB1Ac (%)

7.0 ± 1.5

6.9 ± 0.9

Systolic BP (mmHg)

135.3 ± 18.6

133.0 ± 27.6

Diastolic BP (mmHg)

78.4 ± 8.3

78.7 ± 15.9

Diabetes duration (years)

7.4 ± 6.3

8. 2 ± 7.3

Smokers (%)

49 (23.1)

11 (25)

With Rethinopathy (%)

49 (23.1)

12 (27.3)

Treated with diet (%)

20 (9.6)

5 (11.9)

Treated with oral agents (%)

138 (66)

29 (69.1)

Treated with insulin (%)

51 (24.4)

8 (19)

Treated with ACE or ARB (%)

155 (73.1)

29 (65.9)

Treated with Statins (%)

131 (61.8)

21 (47.7)

Microalbuminuria (%)

62 (29.2)

10 (22.7)

Macroalbuminuria (%)

8 (3.8)

2 (4.5)

GFR < 60 ml/min/ 1.73 m2 (%)

14 (6.7)

3 (7)

  1. BP: Blood pressure UAER: Urinary albumin excretion rate; GFR: glomerular filtration rate.