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Table 5 Cox regression analyses for mortality in the derivation sample

From: The prognostic role of systemic inflammatory markers on HIV-infected patients with non-Hodgkin lymphoma, a multicenter cohort study

Variable Category Univariate analysis Multivariate analysis π
n subjects included = 93
HR (95% CI)* P value HR (95% CI)* P value
Gender Male vs Female 1.03 (0.59-1.79) NS   
Age (years)   1.02 (1.0-1.05) NS   
IDU Yes vs No 1.04 (0.66-1.66) NS   
AIDS defining event Yes vs No 1.73 (1.09-2.73) 0.019 2.02 (1.01-4.02) 0.045
HBV or/and HCV co-infection Yes vs No 0.94 (0.60-1.49) NS   
cART Yes vs No 0.57 (0.35-0.95) 0.032   
CD4 cell count, cell/mm3 <200 vs ≥200 1.79 (1.12-2.88) 0.015   
HIV-RNA undetectable Yes vs No 1.52 (0.84-2.73) NS   
PNI <45 vs ≥45 2.42 (1.22-4.77) 0.011 2.21 (1.11-4.40) 0.023
  1. Abbreviations: HR Hazard Ratio, 95% CI 95% Confidence Interval, IDU Intravenous Drug Use, HBV Hepatitis B Virus, HCV Hepatitis C Virus, cART combined Antiretroviral Therapy, PNI Prognostic Nutritional Index, NS Not Statistical Significant (p > 0.05).
  2. *Adjusted for all the variables in the table. πThe mortality risk score based on the regression coefficients of the variables in final model was represented by 0.703*(AIDS defining event [yes =1/no = 0]) + 0.794 * (PNI) [AIDS defining event within six months from NHL diagnosis].