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Table 3 Effect of xanthine oxidase inhibition by daily oral administration of allopurinol (20 mg.kg −1 , last 4 weeks) on high fructose high fat diet- induced insulin resistance (10% fructose in drinking water plus 25% unsaturated fat in diet, for 12 weeks) associated changes in P, Q, R, S and T amplitudes

From: Xanthine oxidase inhibition alleviates the cardiac complications of insulin resistance: effect on low grade inflammation and the angiotensin system

Treatment P-amplitude (mV) Q-amplitude (mV) R-amplitude (mV) S-amplitude (mV) T-amplitude (mV)
Control −0.011 ± 0.015 −0.134 ± 0.063 0.346 ± 0.077 −0.17 ± 0.07 0.053 ± 0.035
IR 0.057 ± 0.025 −0.18 ± 0.136 0.67 ± 0.148 −0.42 ± 0.21 0.14 ± 0.08
IR-Allo 0.041 ± 0.02 −0.005 ± 0.009 0.527 ± 0.085 −0.28 ± 0.07 0.155 ± 0.046
  1. Values are expressed as the mean ± S.E of mean; N = 6-8 animals; No significant differences were detected by One Way ANOVA.