Table 2 Effect of xanthine oxidase inhibition by daily oral administration of allopurinol (20 mg.kg ⁻¹ , last 4 weeks) on high fructose high fat diet- induced insulin resistance (10% fructose in drinking water plus 25% unsaturated fat in diet, for 12 weeks) associated changes in left ventricle contractility index, heart rate, cycle duration, end systolic pressure (ESP), systolic duration and maximum pressure development (dp/dt)

From: Xanthine oxidase inhibition alleviates the cardiac complications of insulin resistance: effect on low grade inflammation and the angiotensin system